New combo could ease pain after rhinoplasty

NCT ID NCT07380139

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This early-stage trial tests whether adding either dexamethasone or dexmedetomidine to the numbing drug bupivacaine can improve pain control after rhinoplasty (nose job). The study will enroll 90 adults undergoing nose surgery. The main goal is to see how long it takes before patients need their first dose of extra pain medicine after the procedure.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
dexamethasone, dexmedetomidine, bupivacaine
What this could lead to
If it works, this could point toward a better way to manage pain after nose surgery, potentially reducing the need for additional painkillers.
What could go wrong
This is a very early Phase 1 trial with only 90 people, so results may not apply to everyone. The study focuses on timing of pain relief, not long-term outcomes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Ain Shams University

    Cairo, 11122, Egypt

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Other studies related to the condition(s) this trial covers.