Ain Shams University

This study tests whether taking probiotics can lower the chance of atrial fibrillation (an irregular heartbeat) returning after a procedure called cardioversion, which restores normal rhythm. About 56 adults aged 40 and older with persistent AF will take probiotics or a placebo a…

This study tests whether adding N-acetylcysteine (NAC) to standard care helps newborns with sepsis. Sepsis causes dangerous inflammation and cell damage. NAC may reduce this damage by boosting the body's defenses. The trial will enroll 50 near-term and term infants to see if NAC …

This study tests whether adding alpha lipoic acid (a strong antioxidant) to standard chemotherapy helps people with advanced non-small cell lung cancer. About 60 adults with stage III or IV lung cancer will take 600 mg of alpha lipoic acid daily alongside their chemo. Researchers…

This study tests whether adding erythropoietin gel to a standard bone graft helps preserve bone and gum tissue around new dental implants. About 26 adults needing a front tooth implant will be randomly assigned to receive either the gel-plus-graft or graft alone. The main goal is…

This study tests which of two antibiotic combinations works better and is safer for adults with multi-drug resistant (MDR) bacterial infections. About 60 participants will receive either meropenem plus colistin or imipenem/cilastatin plus tigecycline. Researchers will track lab r…

This study tests whether giving tranexamic acid (TXA) through a vein during weight-loss surgery can reduce blood loss in patients with a very high body mass index (BMI over 45). About 128 high-risk adults will receive TXA or a placebo to see if it lowers the need for blood transf…

This study tests if a simple injection of platelet-rich plasma (PRP) can work as well as a common surgery (mid-urethral sling) for women with stress urinary incontinence (leaking urine when coughing or sneezing). About 42 women will be randomly assigned to receive either the PRP …

This study tests whether a supplement called palmitoylethanolamide (PEA) can help people with mild-to-moderate ulcerative colitis. Researchers will measure changes in disease activity, quality of life, and inflammation markers in 60 participants. The goal is to see if adding PEA …

This study tests whether adding venlafaxine, a common antidepressant, to standard rheumatoid arthritis (RA) treatment can better control disease activity. About 70 adults with moderate to severe RA who are already on stable medication will receive either venlafaxine or a placebo …

This study tests whether taking vitamin C and coenzyme Q10 can prevent kidney damage in cancer patients receiving cisplatin chemotherapy. About 75 adults with various cancers who have not had chemo before will take these supplements alongside their treatment. The goal is to see i…

This study tests whether using a special ventilator mode called APRV before removing the breathing tube can improve lung function in severely obese patients after elective heart surgery. About 180 adults with a BMI of 40 or higher will be randomly assigned to receive either APRV …

This study tests whether adding rutin (a plant compound) to vitamin C can lower inflammation and fat buildup in the liver better than vitamin C alone. It involves 120 adults with metabolic fatty liver disease (MASLD) and lasts 12 weeks. The goal is to improve disease control, not…

This study compares two treatments for severely damaged lower molars: a tooth-saving surgery called hemisection (removing the damaged root) versus replacing the whole tooth with a dental implant. Researchers will track 28 participants over 12 months to see which option leads to b…

This study tests whether a dietary supplement called tributyrin can help people with type 2 diabetes better control their blood sugar, reduce inflammation, and lower their risk of heart disease. About 60 adults with type 2 diabetes and a higher heart risk will receive either trib…

This study tests whether adding a special liquid called Theravex to a standard bone graft helps grow more bone for dental implants in the upper jaw. Sixteen adults with low bone height will receive either the standard graft or the graft mixed with Theravex. Researchers will measu…

This study looks at whether a common antioxidant, alpha-lipoic acid (ALA), can help people hospitalized for a sudden worsening of COPD (a lung disease). Researchers will compare a low dose (600 mg) to a high dose (1200 mg) and a placebo, given alongside standard care. The goal is…

This study looks at two ways to fix badly damaged upper back teeth: removing the damaged root (root amputation) or replacing the whole tooth with a dental implant. Researchers will track 28 people over 12 months to see which option leads to less pain, better bone healing, and gre…

This study tests whether adding melatonin, a natural hormone, to the strong antibiotic colistin helps adults with hard-to-treat bacterial infections. These infections are resistant to many drugs and can be life-threatening. The study will compare patients who get melatonin versus…

This study looks at 115 children aged 6 months to 5 years who have a hole in the heart (VSD) and need surgery. Doctors want to see if an ultrasound probe placed in the food pipe (TEE) can measure heart pressure as accurately as the standard method using a thin tube (catheter) ins…

This study will see if artificial intelligence (AI) can help dentists find and assess risky mouth lesions that might turn into cancer. Researchers will take photos and painless cell samples from 120 people with certain mouth conditions. The AI's accuracy will be compared to speci…

This study tests whether the sedative drug dexmedetomidine can prevent new atrial fibrillation (a type of irregular heartbeat) in the days after mitral valve surgery. About 140 adults having this heart surgery will receive the drug or a placebo. The goal is to see if the drug low…

This study tests whether a natural supplement called glutamine can prevent nerve damage caused by the chemotherapy drug vincristine in children and teens with cancer. About 70 participants aged 6 to 18 will receive glutamine for 14 days during treatment. Researchers will track wh…

This study tests whether melatonin, a natural sleep hormone, works as well as midazolam (a common sedative) for calming children before tonsillectomy. About 195 children will receive one of the two medicines before surgery. The goal is to see which one reduces anxiety and confusi…

This study looks at whether adding a nerve block to the back of the hip to two standard front-hip blocks can improve pain relief after hip surgery. About 50 adults having hip surgery will be split into two groups to compare pain scores and the need for extra pain medicine in the …

This study looks at whether adding a medicine called dexamethasone to the usual painkiller (bupivacaine) can better control pain in newborns after inguinal hernia repair. About 150 full-term, healthy babies will take part. Researchers will measure pain using a special scale durin…

This study compares two different medicines placed inside a tooth during a root canal to see which one is better at killing bacteria and reducing pain afterward. About 52 adults with infected single-root teeth will take part. The goal is to find which treatment leads to less disc…

This study tests whether two common antioxidants, N-Acetylcysteine (NAC) and Alpha-Lipoic Acid (ALA), can help reduce pain and the need for strong painkillers after laparoscopic appendix removal. About 180 adults having this surgery will receive one of the antioxidants or a place…

This study compares two common prostate medications, silodosin and tamsulosin, to see which one better relieves moderate to severe urinary symptoms caused by an enlarged prostate. About 140 men aged 50 and older will take each drug for four weeks and report their symptom changes.…

This study looks at 60 myasthenia patients having chest surgery to remove the thymus gland. They will get a nerve block with bupivacaine plus either dexmedetomidine or dexamethasone to see which provides longer pain relief. The goal is to reduce the need for extra pain medication…

This study compares three different surgical techniques for men with enlarged prostates (over 80 grams) who have trouble urinating. The goal is to see which method is safest and works best in the short term. About 105 men will take part and be followed for at least one year after…

This study tests whether a combination of non-opioid pain medicines works as well as fentanyl for children aged 5-10 with mild to moderate sleep apnea who are having their tonsils and adenoids removed. The goal is to control pain with fewer breathing problems and side effects. Si…

This study tests whether a resilience training program can help parents of young children with Down syndrome feel more accepting and less burdened. About 50 parents will be randomly assigned to either the training or usual care. Researchers will measure changes in acceptance, rej…

This study looks at whether avoiding opioids during heart bypass surgery helps elderly patients recover faster. Researchers will compare opioid-free anesthesia to standard opioid-based anesthesia in 60 people aged 65 and older. The goal is to see if this approach reduces time on …

This study compares two suction-assisted methods for removing medium-sized kidney stones (2-3 cm) during a minimally invasive surgery called RIRS. The goal is to see which technique leads to fewer infections and better stone clearance. 126 adults aged 18-60 with kidney stones wil…

This study looks at whether lactoferrin, a protein found in milk, can improve pain control after a planned cesarean section. Ninety women will receive either lactoferrin or a placebo before and after surgery, along with standard pain medicine. The goal is to see if lactoferrin re…

This study tests whether giving gabapentin before bariatric surgery can lower pain levels and reduce the need for extra painkillers in the first 24 hours after surgery. About 102 adults with obesity scheduled for weight-loss surgery will be randomly assigned to receive either gab…

This study compares two types of nerve blocks (ESPB and paravertebral) to see which provides better pain relief after a total abdominal hysterectomy. The goal is to reduce the need for morphine and improve comfort. 48 women aged 30-60 will participate.

This study tests whether a cold anti-inflammatory rinse (ketorolac tromethamine at 2-5°C) placed inside the tooth after root canal can lower post-treatment pain compared to the same rinse at room temperature. Sixty adults with painful tooth infections will rate their pain and hav…

This study compares two ways to fix deep cavities in back teeth that are close to the bone. One method reshapes the gum and bone (crown lengthening), the other builds up the tooth from within (deep margin elevation). Researchers will check gum health and measure a marker of infla…

This study looks at how frailty impacts the quality of life in women aged 60 and older who are newly diagnosed with breast cancer. Researchers will measure changes in well-being and frailty over six months. The goal is to help doctors make better treatment decisions that focus on…

This study looks at whether certain blood markers can predict delirium (sudden confusion) in older adults with heart failure. Researchers will compare two markers: one for inflammation (SII) and one for blood sugar and fat levels (TyG). They aim to find a simple way to identify h…

This study will check if measuring CO2 gap, lactate, and oxygen in the blood can help predict serious problems after heart bypass surgery. About 130 adults having planned bypass surgery will be followed for 7 days after their operation. The goal is to see if these simple tests ca…

This study will compare the accuracy of three different face-scanning techniques—stationary, handheld, and mobile app—for people with facial growths. Sixty volunteers will have their faces scanned with each method, and the results will be compared to a traditional mold. The goal …

This study looks at how cerebral small vessel disease (SVD) — a common age-related condition that damages tiny blood vessels in the brain — affects walking and balance. Researchers will use brain scans (MRI) and EEG recordings to compare brain activity in people with SVD and heal…

This study looks at whether a tool called the LASMAR score can help doctors predict how well surgery to remove uterine fibroids will go. Researchers will check the score against things like surgery time and complications in 88 women. The goal is to see if this score can help plan…

This study looks at whether a weak bladder muscle affects how well prostate surgery works for men with trouble urinating. About 90 men who need a catheter will be split into two groups based on bladder strength. The goal is to see if they can urinate on their own after surgery.

This study looks at how muscle loss (sarcopenia) is related to tiredness and dizziness when standing up in people aged 65 and older. Researchers will compare 90 older adults with and without sarcopenia to see if those with muscle loss feel more tired and have more dizziness. The …