Could a sleep hormone help fight superbugs?
NCT ID NCT07503600
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether adding melatonin to the strong antibiotic colistin helps patients with multidrug-resistant bacterial infections. These infections are hard to treat and often deadly. The trial will give 70 adults either melatonin or a placebo alongside their regular treatment to see if it improves infection control and reduces side effects like kidney damage.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Melatonin
- What this could lead to
- If it works, this could point toward a simple, safe way to boost the effectiveness of last-resort antibiotics for hard-to-treat infections.
- What could go wrong
- This is a small, early-stage trial with only 70 participants. The results may not apply to all patients, and melatonin might not provide significant benefit over placebo.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
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