Could a sleep hormone help fight superbugs?
NCT ID NCT07503600
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether adding melatonin to the strong antibiotic colistin helps patients with multidrug-resistant bacterial infections. These infections are hard to treat and often deadly. The trial will give 70 adults either melatonin or a placebo alongside their regular treatment to see if it improves infection control and reduces side effects like kidney damage.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Melatonin
What this could lead to
If it works, this could point toward a simple, safe way to boost the effectiveness of last-resort antibiotics for hard-to-treat infections.
What could go wrong
This is a small, early-stage trial with only 70 participants. The results may not apply to all patients, and melatonin might not provide significant benefit over placebo.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••