Can antioxidants replace opioids after appendix surgery?
NCT ID NCT07360379
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether two common antioxidants, N-Acetylcysteine (NAC) and Alpha-Lipoic Acid (ALA), can improve pain control and reduce the need for strong painkillers after laparoscopic appendix removal. 180 adults aged 18-65 undergoing this surgery will receive either NAC, ALA, or a placebo alongside standard pain medication. The goal is to see if these supplements can lower pain scores and opioid use in the first two days after surgery.
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