Can antioxidants replace opioids after appendix surgery?

NCT ID NCT07360379

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether two common antioxidants, N-Acetylcysteine (NAC) and Alpha-Lipoic Acid (ALA), can improve pain control and reduce the need for strong painkillers after laparoscopic appendix removal. 180 adults aged 18-65 undergoing this surgery will receive either NAC, ALA, or a placebo alongside standard pain medication. The goal is to see if these supplements can lower pain scores and opioid use in the first two days after surgery.

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Conditions

The condition(s) this trial relates to.

agnosia Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

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