Common sedative may stop dangerous heart rhythm after surgery
NCT ID NCT07482540
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether the sedative drug dexmedetomidine can prevent new-onset atrial fibrillation (a fast, irregular heartbeat) in the days after mitral valve surgery. Researchers will randomly give 140 adults either the drug or a placebo during and after surgery. The goal is to see if the drug lowers the chance of developing this heart rhythm problem, which can cause complications.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Dexmedetomidine
- What this could lead to
- If it works, this could provide a simple way to prevent a common and serious heart rhythm problem after mitral valve surgery.
- What could go wrong
- This is a small, early-stage trial (140 people) that hasn't started recruiting yet. The drug may not reduce AFib risk more than placebo, and side effects like low heart rate are possible.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for ATRIAL FIBRILLATION are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- A tiny neck implant could catch Stroke-Causing clots before they reach the brain
- Could a new injection tame atrial fibrillation?
- Which blood thinner is safer for heart patients? a Head-to-Head test
- Can a cholesterol drug keep atrial fibrillation at bay after ablation?
- Can a One-Two punch fix a leaky heart valve and restore normal rhythm?
- Could a guided Self-Care plan tame atrial Fibrillation's return?