Can a drug combo take the pain out of kidney stents?

NCT ID NCT07562282

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether combining tamsulosin with either a standard or half dose of tadalafil can better relieve symptoms caused by ureteric stents, such as pain, urgency, and discomfort. Researchers will enroll 140 adults who have a stent placed after kidney stone removal. The goal is to see which dose combination works best without causing more side effects.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

tamsulosin and tadalafil

What this could lead to

If it works, this could point toward a better way to manage uncomfortable stent symptoms after kidney stone surgery.

What could go wrong

This is a small, early-phase study with only 140 participants, so results may not apply to everyone. The benefit over existing treatments is uncertain.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Kidney Calculi nephrolithiasis ureterolithiasis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Ain Shams University Hospital

    RECRUITING

    Cairo, Abbasia, Egypt

    Contact Phone: •••-•••-•••• Email: •••••@•••••