PERSISTENT ATRIAL FIBRILLATION

This study is observing how well a specific heart ablation device works over three years for people with persistent atrial fibrillation that hasn't responded to medication. About 200 participants will have the ablation procedure and be followed to see if their irregular heart rhy…

This study is collecting real-world safety and effectiveness data on a balloon catheter device used to treat two types of atrial fibrillation (AFib). It will enroll 300 adults with symptomatic AFib who haven't responded well to medication. The main goals are to track serious comp…

This study is testing whether adding extra ablation lines to the standard pulmonary vein isolation procedure works better for controlling persistent atrial fibrillation. Researchers will randomly assign 640 participants to receive either the standard procedure or the expanded pro…

This is the first human trial of a new catheter designed to treat persistent atrial fibrillation (AFib), a long-lasting irregular heartbeat. The catheter can change shape to deliver targeted electrical pulses to scar small areas of heart tissue, aiming to block the faulty electri…

This study is testing a new medical device system designed to treat a common type of irregular heartbeat called atrial fibrillation (AFib). The procedure uses pulsed electrical fields to scar heart tissue and block faulty electrical signals. Researchers aim to see if this new sys…

This study is testing whether a lower dose of the heart rhythm drug amiodarone (100 mg/day) works as well as the standard dose (200 mg/day) to keep the heart in a normal rhythm after treatment for persistent atrial fibrillation. It aims to see if the lower dose can control the co…

This study is testing the safety and effectiveness of two handheld surgical devices that use extreme cold or radiofrequency energy to create scar tissue in the heart. The goal is to stop or reduce persistent irregular heartbeats (atrial fibrillation) in patients who are already h…

This study is testing whether a newer, two-part 'hybrid' heart procedure works better than the standard catheter procedure for people who have both a long-lasting irregular heartbeat (persistent atrial fibrillation) and heart failure. About 120 participants will be randomly assig…

This study is testing new electrical waveforms delivered through the FARAPULSE system to treat atrial fibrillation, a common irregular heartbeat condition. Researchers will enroll 200 adults with either occasional or persistent atrial fibrillation to evaluate the safety and effec…

This study is testing a new heart mapping system designed to help doctors better target treatment for persistent atrial fibrillation (AFib), a common irregular heartbeat. The research will see if using this detailed map to guide a standard ablation procedure is safe and more effe…

This study is testing a new medical device called the FARAFLEX system for people with persistent or paroxysmal atrial fibrillation (AFib), a condition causing irregular heartbeats. The procedure uses pulsed field ablation, a newer type of energy, to create small scars in the hear…

This study is testing whether a heart procedure called catheter ablation, when added to standard medication, can help improve or stabilize thinking and memory in older adults who have both a persistent irregular heartbeat (atrial fibrillation) and mild cognitive impairment. About…

This study is testing whether adding a special ultrasound treatment to the kidneys during a repeat heart procedure helps prevent atrial fibrillation (AFib) from returning. It involves 250 adults with high blood pressure whose AFib has come back after a previous procedure. Partici…

This study is testing a recently approved pulsed field ablation system for treating atrial fibrillation in typical patients seen in regular medical practice. The procedure uses electrical pulses to create scar tissue in the heart to block irregular electrical signals. Researchers…

This study is testing three different approaches to catheter ablation, a procedure that uses energy to create small scars in heart tissue, to control persistent atrial fibrillation (AFib). Researchers are comparing how well each method prevents the return of irregular heart rhyth…

This study is testing a specialized catheter system that uses pulsed electrical fields to treat persistent atrial fibrillation (AFib) in people whose first procedure didn't work. The goal is to see if this second procedure is safe and effective at stopping the irregular heartbeat…

This study compares two common treatments for persistent atrial fibrillation (AF), an irregular heart rhythm. Researchers want to see if catheter ablation (a procedure that scars heart tissue to block faulty electrical signals) works better than electrical cardioversion (a contro…

This study is testing a new paddle-shaped catheter designed to create detailed maps of irregular heartbeats. The device will be used in 60 patients with conditions like atrial fibrillation and ventricular tachycardia who are already scheduled for a heart procedure. Researchers wa…

This is a small pilot study to see if it's practical to run a larger trial on how short-term exercise affects symptoms in people with atrial fibrillation (AF). Researchers will enroll 36 symptomatic men and women with AF. Participants will try a week of moderate exercise, a week …