PERSISTENT ATRIAL FIBRILLATION
Clinical trials for PERSISTENT ATRIAL FIBRILLATION explained in plain language.
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New heart procedure aims to tame atrial fibrillation without drugs
Disease control CompletedThis study tested a new device called the Volt PFA System, which uses pulsed field ablation to treat atrial fibrillation (AF), a common heart rhythm problem. Researchers enrolled 392 people with symptomatic AF that didn't respond to medication. The goal was to see if the procedur…
Matched conditions: PERSISTENT ATRIAL FIBRILLATION
Phase: NA • Sponsor: Abbott Medical Devices • Aim: Disease control
Last updated Jun 27, 2026 12:29 UTC
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New heart zapping tech tested for stubborn AFib
Disease control CompletedThis study tested two new devices that use energy pulses to treat persistent atrial fibrillation (a type of irregular heartbeat). 89 adults who had not responded to medication received a heart ablation procedure. The goal was to see if the devices are safe and can stop abnormal h…
Matched conditions: PERSISTENT ATRIAL FIBRILLATION
Phase: NA • Sponsor: Adagio Medical • Aim: Disease control
Last updated Jun 27, 2026 12:06 UTC
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New freezing device tackles stubborn heart rhythm disorder
Disease control CompletedThis study tested a device called iCLAS™ that uses extreme cold to destroy tiny areas of heart tissue causing persistent atrial fibrillation (AFib). 215 adults with AFib lasting more than 7 days but less than a year received the procedure. Researchers tracked safety issues like h…
Matched conditions: PERSISTENT ATRIAL FIBRILLATION
Phase: NA • Sponsor: Adagio Medical • Aim: Disease control
Last updated Jun 27, 2026 12:06 UTC
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New 12-step heart ablation method aims to keep irregular heartbeat away longer
Disease control CompletedThis study tested a systematic 12-step workflow for a newer type of heart ablation (pulsed-field ablation) in 118 adults with atrial fibrillation. The goal was to see if this approach could better isolate the pulmonary veins and reduce the chance of the heart rhythm problem retur…
Matched conditions: PERSISTENT ATRIAL FIBRILLATION
Sponsor: Daniel Rodríguez Muñoz • Aim: Disease control
Last updated Jun 27, 2026 12:01 UTC
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New heart zapping device shows promise for stubborn AFib
Disease control CompletedThis study tested the FARAPULSE system, a device that uses short electrical pulses to destroy small areas of heart tissue causing abnormal rhythms in people with persistent atrial fibrillation (AFib). The trial enrolled 669 adults with drug-resistant, symptomatic persistent AFib.…
Matched conditions: PERSISTENT ATRIAL FIBRILLATION
Phase: NA • Sponsor: Boston Scientific Corporation • Aim: Disease control
Last updated Jun 27, 2026 08:04 UTC
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New ablation combo may keep AFib at bay longer
Disease control CompletedThis study tested whether adding ablation of the left atrial posterior wall to standard pulmonary vein isolation reduces the return of atrial fibrillation in people with persistent AF. A total of 110 adults having their first catheter ablation took part. The goal was to see if th…
Matched conditions: PERSISTENT ATRIAL FIBRILLATION
Phase: NA • Sponsor: Arash Aryana, MD • Aim: Disease control
Last updated Jun 27, 2026 07:56 UTC
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New heart procedure aims to stop persistent AFib without pills
Disease control CompletedThis study tested a device called the DiamondTemp system, which uses heat energy to destroy tiny areas of heart tissue causing irregular heartbeats in people with persistent atrial fibrillation. 376 adults with drug-resistant symptoms took part. The goal was to see if the procedu…
Matched conditions: PERSISTENT ATRIAL FIBRILLATION
Phase: NA • Sponsor: Medtronic Cardiac Ablation Solutions • Aim: Disease control
Last updated Jun 27, 2026 07:55 UTC
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New heart ablation method aims to beat atrial fibrillation
Disease control CompletedThis study tested whether adding a personalized, computer-model-guided ablation (OPTIMA) to the standard pulmonary vein isolation (PVI) procedure improves outcomes for people with persistent atrial fibrillation. 67 participants were randomly assigned to receive either PVI alone o…
Matched conditions: PERSISTENT ATRIAL FIBRILLATION
Phase: NA • Sponsor: Johns Hopkins University • Aim: Disease control
Last updated Jun 27, 2026 07:54 UTC
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New heart mapping tech tested for AFib treatment
Disease control CompletedThis study tested a new mapping feature (FARAVIEW™) used with a pulsed field ablation catheter (FARAWAVE NAV™) to treat atrial fibrillation. Fifty patients with symptomatic AFib that didn't respond to medication were included. The goal was to see how well doctors could isolate th…
Matched conditions: PERSISTENT ATRIAL FIBRILLATION
Phase: NA • Sponsor: Boston Scientific Corporation • Aim: Disease control
Last updated Jun 26, 2026 17:41 UTC
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Freeze or pills? new study battles persistent AF
Disease control CompletedThis study compared two treatments for persistent atrial fibrillation (an irregular heartbeat): cryoablation (freezing tiny areas of heart tissue) and antiarrhythmic drugs. 196 patients were randomly assigned to one treatment and monitored for over a year. The goal was to see whi…
Matched conditions: PERSISTENT ATRIAL FIBRILLATION
Phase: PHASE4 • Sponsor: Hospital San Carlos, Madrid • Aim: Disease control
Last updated Jun 26, 2026 16:56 UTC
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Heart rhythm showdown: which ablation strategy wins for persistent AF?
Disease control CompletedThis study tested two ways to treat persistent atrial fibrillation (a type of irregular heartbeat) using catheter ablation. In one group, doctors aimed to stop the abnormal rhythm during the procedure. In the other, they followed a preset plan and used electrical shock if needed.…
Matched conditions: PERSISTENT ATRIAL FIBRILLATION
Phase: NA • Sponsor: Shanghai Chest Hospital • Aim: Disease control
Last updated Jun 26, 2026 16:33 UTC
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Personalized heart ablation may beat standard procedure for AFib
Disease control CompletedThis study tested whether a tailored ablation approach, which targets specific abnormal areas in the heart, works better than the standard anatomical ablation for people with persistent atrial fibrillation (AFib). 377 adults with AFib that didn't respond to medication were includ…
Matched conditions: PERSISTENT ATRIAL FIBRILLATION
Phase: NA • Sponsor: Volta Medical • Aim: Disease control
Last updated Jun 26, 2026 16:02 UTC
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New heart mapping algorithm aims to tame chaotic rhythms
Symptom relief CompletedThis study tested a computer algorithm called CartoFinder to help doctors better identify and treat complex heart rhythm problems (arrhythmias). 70 adults with persistent atrial fibrillation (a type of irregular heartbeat) took part. The goal was to see if the algorithm could imp…
Matched conditions: PERSISTENT ATRIAL FIBRILLATION
Phase: NA • Sponsor: Biosense Webster, Inc. • Aim: Symptom relief
Last updated Jun 27, 2026 14:00 UTC
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Small study tests if exercise eases heart flutter symptoms
Knowledge-focused CompletedThis pilot study looked at whether it's possible to run a larger trial comparing two types of exercise—moderate steady exercise and high-intensity interval training—on symptoms of atrial fibrillation (AF), a common heart rhythm problem. Researchers enrolled 25 men and women with …
Matched conditions: PERSISTENT ATRIAL FIBRILLATION
Phase: NA • Sponsor: Ottawa Heart Institute Research Corporation • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:03 UTC
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Second ablation may zap hidden heart triggers
Knowledge-focused CompletedThis study looked at 44 people with persistent atrial fibrillation who had a second heart procedure 2 months after their first ablation. Doctors checked for reconnections in the pulmonary veins and treated them again to see if this improves outcomes. The goal was to better unders…
Matched conditions: PERSISTENT ATRIAL FIBRILLATION
Phase: NA • Sponsor: Liverpool Heart and Chest Hospital NHS Foundation Trust • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:01 UTC
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New algorithm could sharpen view of chaotic heart rhythms during ablation
Knowledge-focused CompletedThis completed study tested a new algorithm that automatically measures the cycle length and complexity of atrial fibrillation (AF) signals during a heart ablation procedure. Researchers collected data from 21 people with persistent AF undergoing ablation. The goal was to see if …
Matched conditions: PERSISTENT ATRIAL FIBRILLATION
Sponsor: CathVision ApS • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:00 UTC
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New algorithm tested to improve heart ablation for AFib
Knowledge-focused CompletedThis study tested a new computer algorithm that analyzes heart signals during a procedure called ablation for persistent atrial fibrillation (a type of irregular heartbeat). The goal was to see if the system could collect and process these signals to help doctors better understan…
Matched conditions: PERSISTENT ATRIAL FIBRILLATION
Sponsor: CathVision ApS • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:04 UTC
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Heart rhythm mystery: new study maps hidden triggers of persistent AF
Knowledge-focused CompletedThis study looked at 17 adults with persistent atrial fibrillation (a long-lasting heart rhythm problem) to find specific areas in the heart that may keep the condition going. Researchers used special mapping to identify stable high-frequency electrical signals. The goal was to b…
Matched conditions: PERSISTENT ATRIAL FIBRILLATION
Sponsor: University of Leicester • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:52 UTC