PERSISTENT ATRIAL FIBRILLATION

This study tests whether a procedure called pulsed field ablation (PFA) is safer and more effective than anti-arrhythmic drugs as a first treatment for people with persistent atrial fibrillation (a type of irregular heartbeat). About 484 adults with symptomatic persistent AFib wi…

This study compares two ablation techniques for people with persistent atrial fibrillation (a type of irregular heartbeat). One method isolates the pulmonary veins, while the other also targets additional areas in the heart. The goal is to see which approach better prevents the r…

This study tests a new device called the Globe Pulsed Field System to treat people with atrial fibrillation (AF), a common heart rhythm problem. The device uses short electrical pulses to correct the heart's rhythm. The study includes 549 adults with AF who have not responded wel…

This study follows 400 adults with persistent atrial fibrillation (a type of irregular heartbeat) who are treated with a procedure called cryoablation. The procedure uses a special catheter to freeze small areas of heart tissue that cause the abnormal rhythm. Researchers want to …

This study tests a new system that uses short bursts of energy to fix irregular heartbeats (atrial fibrillation) in 300 people. The goal is to see if it safely restores a normal rhythm without needing lifelong medication. Participants have symptoms that haven't improved with drug…

This study follows 200 adults with persistent atrial fibrillation (a type of irregular heartbeat lasting more than 7 days but less than a year) who are treated with the Sphere-9 catheter and Affera ablation system. The goal is to see if the procedure safely prevents the return of…

This study tests a catheter-based procedure to treat people with persistent or long-standing atrial fibrillation (a type of irregular heartbeat). The procedure uses energy to isolate parts of the heart and create controlled scars to restore normal rhythm. Researchers will track 5…

This study tests if adding extra ablation to the standard procedure helps people with persistent atrial fibrillation (a long-lasting irregular heartbeat) stay in normal rhythm. About 206 adults will be randomly assigned to receive either standard pulmonary vein isolation or that …

This early study tests a new balloon-shaped catheter that uses pulsed electric fields to treat persistent atrial fibrillation, a type of irregular heartbeat. 34 adults aged 18-75 with persistent AF will undergo the procedure and be followed for 12 months to check safety and how w…

This study compares two techniques—radiofrequency and pulsed field ablation—to treat persistent atrial fibrillation, a heart rhythm disorder. About 50 adults with the condition will receive one of the two procedures. The goal is to see which method better creates lasting isolatio…

This study evaluates the FARAPULSE system, a catheter-based device that uses pulsed electric fields to treat atrial fibrillation (an irregular heartbeat). About 275 adults with this condition will undergo a standard ablation procedure using this system. The goal is to see if it s…

This study looks at 300 adults with both persistent atrial fibrillation (a long-lasting irregular heartbeat) and heart failure. Researchers are testing different catheter ablation strategies to see which one works best to prevent heart-related death, hospital stays, or urgent vis…

This pilot study explores whether advanced ECG mapping and enhanced MRI/PET scans can identify the exact areas causing persistent atrial fibrillation (AF) and guide a more targeted catheter ablation. Researchers aim to see if this personalized approach leads to higher success in …