Simple IV fluids may shield kidneys during new heart ablation technique

NCT ID NCT07490808

First seen Jun 25, 2026 · Last updated Aug 14, 2026 · Updated 2 times

Summary

This study tests whether giving extra fluids (saline) through an IV during and after a heart procedure called pulsed field ablation can prevent acute kidney injury. The procedure is used to treat atrial fibrillation, a common heart rhythm problem, but can sometimes harm the kidneys. About 290 adults with atrial fibrillation will be randomly assigned to receive either the extra fluids or standard care. The main goal is to see if hydration reduces the chance of kidney damage while in the hospital.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
0.9% sodium chloride (saline) given intravenously
What this could lead to
If it works, this could provide a simple, low-cost way to protect kidneys during pulsed field ablation for atrial fibrillation.
What could go wrong
This is a small, early-stage trial at one center. The hydration strategy may not reduce kidney injury and could cause fluid overload in some patients.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Beijing Anzhen Hospitai, Capital Medical University

    Beijing, Beijing Municipality, 100029, China

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