New heart-zapping technique tested to improve irregular heartbeat treatment

NCT ID NCT05986526

Ongoing Disease control Sponsor: Insel Gruppe AG, University Hospital Bern Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 28, 2026 · Updated 2 times

Summary

This study tests whether adding extra ablation to the back wall of the heart's left atrium improves outcomes for people with persistent atrial fibrillation (a type of irregular heartbeat). About 206 participants will receive either standard vein isolation or vein isolation plus back-wall ablation using a newer, safer energy method called pulsed-field ablation. The goal is to see which approach better prevents heart rhythm problems over one year.

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Conditions

The condition(s) this trial relates to.

atrial fibrillation persistent atrial fibrillation

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PERSISTENT ATRIAL FIBRILLATION

Contacts and locations

Locations

Cantonal Hospital Baden

Baden, Switzerland
Cantonal Hospital St. Gallen

Sankt Gallen, Switzerland
Inselspital, University Hospital Bern

Bern, 3010, Switzerland
University Hospital Basel

Basel, Switzerland
University Hospital Lausanne

Lausanne, 1011, Switzerland
University Hospital Zürich

Zurich, Switzerland

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