Freezing away heart flutters: new study tests Long-Term control of persistent AF

NCT ID NCT05005949

First seen Nov 13, 2025 · Last updated Jun 13, 2026 · Updated 23 times

Summary

This study looks at a procedure called cryoablation that uses a freezing balloon to destroy tiny areas of heart tissue causing an irregular heartbeat (persistent atrial fibrillation). About 400 adults with this condition will be followed for up to 3 years to see how well the treatment prevents the abnormal rhythm from coming back and to check for any safety issues. The goal is to control the disease, not cure it, since ongoing management may still be needed.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • BayCare Medical Group Cardiology

    Clearwater, Florida, 33756, United States

  • Cardiology Associates of Fairfield County

    Stamford, Connecticut, 06905-5522, United States

  • Carle Foundation Hospital

    Urbana, Illinois, 61801-2500, United States

  • Centralny Szpital Kliniczny Uniwersytetu Medycznego w Łodz

    Lodz, 92-213, Poland

  • Hartford Hospital

    Hartford, Connecticut, 06102, United States

  • Heart Rhythms Solutions

    Davie, Florida, 33328, United States

  • Henry Ford Heart & Vascular

    Detroit, Michigan, 48202-2608, United States

  • Kepler Universitätsklinikum Med Campus III.

    Linz, 4020, Austria

  • Liverpool Heart and Chest Hospital NHS Foundation Trust

    Liverpool, L14 3PE, United Kingdom

  • MVZ CCB Frankfurt und Main Taunus

    Frankfurt am Main, 60431, Germany

  • Spectrum Health Hospitals

    Grand Rapids, Michigan, 49525-6427, United States

  • St. Vinzenz-Hospital Köln

    Cologne, 50733, Germany

  • Städtische Kliniken München GmbH - Klinikum Bogenhausen

    München, 81925, Germany

  • Texas Cardiac Arrhythmia Research Foundation

    Austin, Texas, 78705-1852, United States

  • Texas Health Research & Education Institute

    Dallas, Texas, 75231, United States

  • The Lindner Research Center

    Cincinnati, Ohio, 45219-2906, United States

  • Universitaria Pisana - Stabilimento di Cisanello

    Pisa, 56124, Italy

Conditions

Explore the condition pages connected to this study.