Freezing away heart flutters: new study tests Long-Term control of persistent AF
NCT ID NCT05005949
First seen Jun 27, 2026 · Last updated Jul 23, 2026 · Updated 2 times
Summary
This study looks at a procedure called cryoablation that uses a freezing balloon to destroy tiny areas of heart tissue causing an irregular heartbeat (persistent atrial fibrillation). About 400 adults with this condition will be followed for up to 3 years to see how well the treatment prevents the abnormal rhythm from coming back and to check for any safety issues. The goal is to control the disease, not cure it, since ongoing management may still be needed.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for PERSISTENT ATRIAL FIBRILLATION are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
BayCare Medical Group Cardiology
Clearwater, Florida, 33756, United States
-
Cardiology Associates of Fairfield County
Stamford, Connecticut, 06905-5522, United States
-
Carle Foundation Hospital
Urbana, Illinois, 61801-2500, United States
-
Centralny Szpital Kliniczny Uniwersytetu Medycznego w Łodz
Lodz, 92-213, Poland
-
Hartford Hospital
Hartford, Connecticut, 06102, United States
-
Heart Rhythms Solutions
Davie, Florida, 33328, United States
-
Henry Ford Heart & Vascular
Detroit, Michigan, 48202-2608, United States
-
Kepler Universitätsklinikum Med Campus III.
Linz, 4020, Austria
-
Liverpool Heart and Chest Hospital NHS Foundation Trust
Liverpool, L14 3PE, United Kingdom
-
MVZ CCB Frankfurt und Main Taunus
Frankfurt am Main, 60431, Germany
-
Spectrum Health Hospitals
Grand Rapids, Michigan, 49525-6427, United States
-
St. Vinzenz-Hospital Köln
Cologne, 50733, Germany
-
Städtische Kliniken München GmbH - Klinikum Bogenhausen
München, 81925, Germany
-
Texas Cardiac Arrhythmia Research Foundation
Austin, Texas, 78705-1852, United States
-
Texas Health Research & Education Institute
Dallas, Texas, 75231, United States
-
The Lindner Research Center
Cincinnati, Ohio, 45219-2906, United States
-
Universitaria Pisana - Stabilimento di Cisanello
Pisa, 56124, Italy
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can a cholesterol drug keep atrial fibrillation at bay after ablation?
- Which ablation method best tames persistent AF? a Head-to-Head trial aims to find out
- Extra ablation target may cut AF recurrence in persistent cases
- New heart ablation tech under scrutiny: can it tame dangerous rhythms?
- New 3D heart imaging could sharpen ablation precision
- More zaps, better rhythm? trial tests extra ablations for AFib