New heart procedure aims to improve rhythm control in persistent AF patients
NCT ID NCT05922917
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests two different ablation techniques using a new, safer method called pulsed-field ablation (PFA) in 300 adults with persistent atrial fibrillation (a type of irregular heartbeat). One group gets standard vein isolation, while the other gets additional targeted burns in the heart. The goal is to see which approach better prevents the return of irregular heartbeats over 12 months.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Ceske Budejovice Hospital
České Budějovice, 37001, Czechia
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Institute for Clinical and Experimental Medicine
Prague, 14037, Czechia
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University Hospital
Olomouc, 77900, Czechia
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Which ablation method best tames persistent AF? a Head-to-Head trial aims to find out
- Extra ablation target may cut AF recurrence in persistent cases
- New heart ablation technique could tame dangerous rhythms in adults born with heart defects
- New heart ablation tech under scrutiny: can it tame dangerous rhythms?