New heart procedure aims to tame stubborn atrial fibrillation

NCT ID NCT07446244

ENROLLING_BY_INVITATION Disease control Sponsor: University Medical Centre Ljubljana Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a catheter ablation procedure for people with persistent or long-standing persistent atrial fibrillation, a type of irregular heartbeat that is hard to treat. The procedure uses electroporation and radiofrequency energy to create scars in the heart that block abnormal signals. Researchers will check if it is safe and effective by monitoring heart rhythm over a year in 50 participants.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: catheter ablation procedure using electroporation and radiofrequency energy
What this could lead to: If successful, this could offer a more effective way to control persistent atrial fibrillation and reduce the need for long-term medication.
What could go wrong: This is a small, early feasibility study with only 50 participants, so results may not apply to everyone. The procedure carries risks like bleeding, infection, or heart rhythm problems.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

atrial fibrillation persistent atrial fibrillation

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PERSISTENT ATRIAL FIBRILLATION PERSISTENT ATRIAL FIBRILLATION LONGSTANDING

Contacts and locations

Locations

University Medical Centre Ljubljana

Ljubljana, Osrednjaslovenska, 1000, Slovenia

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