New Imaging-Guided ablation aims to stop stubborn AFib
NCT ID NCT02184013
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This pilot study tests whether using advanced imaging (ECGI, MRI, and PET scans) to identify abnormal heart tissue and electrical circuits can improve catheter ablation for persistent atrial fibrillation. Fifty-two adults with persistent AF who have not had prior ablation will receive a tailored procedure. The main goal is to see if this approach can stop AF during the procedure and reduce recurrence afterward.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
catheter ablation guided by ECGI mapping and atrial fibrosis mapping (DE-MRI)
What this could lead to
If successful, this approach could improve success rates for catheter ablation in patients with persistent atrial fibrillation, reducing recurrence.
What could go wrong
This is a small pilot study (52 participants) with no control group, so results may not be generalizable. The procedure carries standard risks of catheter ablation, such as bleeding or heart damage.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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University of Ottawa Heart Institute
Ottawa, Ontario, K1Y 4W7, Canada