Smartwatch study could change how millions take blood thinners

NCT ID NCT05836987

Recruiting now Disease control Sponsor: Johns Hopkins University Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests if people with atrial fibrillation (an irregular heartbeat) can use a smartwatch to decide when to take blood thinners, instead of taking them every day. About 5,350 adults with a low-to-moderate stroke risk will be randomly assigned to either standard daily blood thinners or smartwatch-guided, short-term use. The goal is to see if the smartwatch approach is just as good at preventing strokes while causing fewer bleeding problems.

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Conditions

The condition(s) this trial relates to.

atrial fibrillation Ischemic Stroke paroxysmal atrial fibrillation persistent atrial fibrillation

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ATRIAL FIBRILLATION

Contacts and locations

Locations

Advanced Heart and Vascular Institute of Hunterdon
RECRUITING

Flemington, New Jersey, 08822, United States
Alexian Brothers Health System
RECRUITING

Elk Grove Village, Illinois, 60007, United States
Allegheny Singer Research Institute
RECRUITING

Pittsburgh, Pennsylvania, 15212, United States
Ascension St. Vincent
RECRUITING

Indianapolis, Indiana, 46260, United States
BMC - Brighton
RECRUITING

Boston, Massachusetts, 02135, United States
Banner University
RECRUITING

Phoenix, Arizona, 85006, United States
BayCare Health Systems
RECRUITING

Clearwater, Florida, 33759, United States
Baycare Health Systems Clearwater
RECRUITING

Winter Haven, Florida, 33881, United States
Baylor College of Medicine
RECRUITING

Houston, Texas, 77030, United States
Beth Israel Deaconess Medical Center
RECRUITING

Boston, Massachusetts, 02215, United States
Boston Medical Center
RECRUITING

Boston, Massachusetts, 02118, United States
Brigham and Women's Hospital
RECRUITING

Boston, Massachusetts, 02115, United States
Cardiology Consultants of Philadelphia
NOT_YET_RECRUITING

Paoli, Pennsylvania, 19301, United States
Cleveland Clinic Florida
WITHDRAWN

Stuart, Florida, 34994, United States
Columbia University Medical Center
RECRUITING

New York, New York, 10032, United States
Corewell Health (Former Spectrum Health)
RECRUITING

Grand Rapids, Michigan, 49503, United States
Emory University
RECRUITING

Atlanta, Georgia, 30332, United States
Essentia Health The Duluth Clinic
ACTIVE_NOT_RECRUITING

Duluth, Minnesota, 55812, United States
Georgia Arrhythmia Consultants and Research Institute
RECRUITING

Warner Robins, Georgia, 31093, United States
Hackensack Meridian Health
RECRUITING

Hackensack, New Jersey, 07601, United States
Hennepin Healthcare Research Institute
RECRUITING

Minneapolis, Minnesota, 55415, United States
Henry Ford Health
RECRUITING

Detroit, Michigan, 48202, United States
Houston Methodist Hospital
RECRUITING

Houston, Texas, 77030, United States
James River Cardiology
RECRUITING

Richmond, Virginia, 23229, United States
Johns Hopkins Univeristy
RECRUITING

Baltimore, Maryland, 21218, United States
Kaiser Permanente
NOT_YET_RECRUITING

San Francisco, California, 94115, United States
Lahey Hospital & Medical Center
RECRUITING

Burlington, Massachusetts, 01805, United States
Loyola University Chicago
RECRUITING

Chicago, Illinois, 60660, United States
MUSC Health Heart and Vascular
RECRUITING

Columbia, South Carolina, 29204, United States
Maine Medical Partners MaineHealth Cardiology
RECRUITING

Scarborough, Maine, 04074, United States
Mass General Hospital
NOT_YET_RECRUITING

Boston, Massachusetts, 02114, United States
Mayo Clinic
RECRUITING

Jacksonville, Florida, 32224, United States
Medical College of Wisconsin Froedtert Hospital
RECRUITING

Milwaukee, Wisconsin, 53226, United States
Medical Faculty Associates George Washington University
WITHDRAWN

Washington D.C., District of Columbia, 20037, United States
Medical University of South Carolina
RECRUITING

Charleston, South Carolina, 29425, United States
Midwest Cardiovascular Institute
RECRUITING

Naperville, Illinois, 60540, United States
Minneapolis Heart Institute Foundation
RECRUITING

Minneapolis, Minnesota, 55407, United States
NYU Langone Health
RECRUITING

New York, New York, 10016, United States
NewYork Presbyterian - Queens
RECRUITING

Queens, New York, 11355, United States
NorthShore University HealthSystem
RECRUITING

Evanston, Illinois, 60201, United States
Northwestern University
RECRUITING

Chicago, Illinois, 60611, United States
Ohio State University Medical Center
RECRUITING

Columbus, Ohio, 43210, United States
OhioHealth Research Institute
RECRUITING

Columbus, Ohio, 43214, United States
Penn State Health Medical Group Berks Cardiology
RECRUITING

Wyomissing, Pennsylvania, 19610, United States
Presbyterian Healthcare Services
ACTIVE_NOT_RECRUITING

Albuquerque, New Mexico, 87106, United States
Rhode Island Hospital
RECRUITING

Providence, Rhode Island, 02903, United States
Rush University Medical Center
RECRUITING

Chicago, Illinois, 60612, United States
Rutgers, the State University of New Jersey
RECRUITING

Piscataway, New Jersey, 08854, United States
Sarasota Memorial Health Care System
RECRUITING

Sarasota, Florida, 34236, United States
Scripps Health
RECRUITING

San Diego, California, 92103, United States
South Denver Cardiology Associates, P.C.
RECRUITING

Littleton, Colorado, 80120, United States
St. Elizabeth's Medical Center
RECRUITING

Washington D.C., District of Columbia, 20032, United States
St. Joseph Medical Center Tacoma
RECRUITING

Tacoma, Washington, 98405, United States
Stanford University
RECRUITING

Stanford, California, 94305, United States
Staten Island University Hospital-Northwell Health
RECRUITING

Staten Island, New York, 10305, United States
Stony Brook University
RECRUITING

Stony Brook, New York, 11794, United States
Texas Cardiac Arrhythmia Research Foundation
RECRUITING

Austin, Texas, 78705, United States
The Lindner Center for Research and Education at The Christ Hospital
RECRUITING

Cincinnati, Ohio, 45219, United States
The Valley Hospital, Inc.
RECRUITING

Ridgewood, New Jersey, 07450, United States
Thomas Jefferson University
RECRUITING

Philadelphia, Pennsylvania, 19144, United States
Trinity Health Grand Rapids/Mercy Health
RECRUITING

Grand Rapids, Michigan, 49503, United States
Trinity Health Michigan Heart - Ann Arbor
RECRUITING

Ypsilanti, Michigan, 48197, United States
Tufts Medical Center
RECRUITING

Boston, Massachusetts, 02111, United States
UC Davis Health
RECRUITING

Sacramento, California, 95817, United States
UMass Chan Medical School
ACTIVE_NOT_RECRUITING

Worcester, Massachusetts, 01655, United States
University Health Truman Medical Center
WITHDRAWN

Kansas City, Missouri, 64108, United States
University at Buffalo
RECRUITING

Buffalo, New York, 14214, United States
University of California Los Angeles (UCLA Health)
RECRUITING

Los Angeles, California, 90095, United States
University of Chicago
RECRUITING

Chicago, Illinois, 60637, United States
University of Cincinnati College of Medicine
RECRUITING

Cincinnati, Ohio, 45267, United States
University of Colorado
RECRUITING

Aurora, Colorado, 80045, United States
University of Florida
RECRUITING

Gainesville, Florida, 32611, United States
University of Illinois Chicago
RECRUITING

Chicago, Illinois, 60607, United States
University of Iowa Hospitals and Clinics
RECRUITING

Iowa City, Iowa, 52242, United States
University of Miami - Leonard S. Miller SOM
RECRUITING

Miami, Florida, 33136, United States
University of Minnesota
RECRUITING

Minneapolis, Minnesota, 55455, United States
University of New Mexico Health Sciences Center
RECRUITING

Albuquerque, New Mexico, 87102, United States
University of North Carolina
RECRUITING

Chapel Hill, North Carolina, 27599, United States
University of Oklahoma Health Sciences Center
RECRUITING

Oklahoma City, Oklahoma, 73104, United States
University of Southern California - Keck School of Medicine
RECRUITING

Los Angeles, California, 90033, United States
University of Texas Health Science Center at Houston
RECRUITING

Houston, Texas, 77030, United States
University of Texas Southwestern Medical Center
RECRUITING

Dallas, Texas, 75390, United States
University of Utah
RECRUITING

Salt Lake City, Utah, 84112, United States
University of Virginia
RECRUITING

Charlottesville, Virginia, 22903, United States
University of Wisconsin
RECRUITING

Madison, Wisconsin, 53706, United States
Virginia Commonwealth University
RECRUITING

Richmond, Virginia, 23284, United States
Wake Forest Baptist Health
RECRUITING

Winston-Salem, North Carolina, 27157, United States
Washington University School of Medicine
RECRUITING

St Louis, Missouri, 63110, United States
Weill Medical College of Cornell University
RECRUITING

New York, New York, 10065, United States
Westchester Medical Center
RECRUITING

Valhalla, New York, 10595, United States
White Plains Hospital
RECRUITING

White Plains, New York, 10601, United States
William Beaumont Hospital
RECRUITING

Royal Oak, Michigan, 48073, United States
Wooster Community Hospital
RECRUITING

Wooster, Ohio, 44691, United States

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