Shape-Shifting catheter takes on stubborn heart rhythm disorder

NCT ID NCT07301190

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This early study tests a new catheter that changes shape to better treat persistent atrial fibrillation (AF), a type of irregular heartbeat. The catheter can switch between a large 'petal' shape for quick vein isolation and a small 'bud' shape for precise linear ablation. Forty adults with persistent AF will undergo the procedure and be monitored for a year to see if it's safe and creates lasting effects.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

PFLotus catheter (pulsed field ablation device)

What this could lead to

If it works, this could offer a more flexible and effective way to treat persistent atrial fibrillation with a single device.

What could go wrong

This is a very early, small trial with only 40 people. It's designed mainly to check safety and short-term results, not to prove long-term benefit. The procedure carries risks like bleeding, heart damage, or stroke.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

atrial fibrillation persistent atrial fibrillation

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • The Third People's Hospital of Chengdu

    RECRUITING

    Chengdu, China