Nerve-Zapping kidney procedure may boost heart rhythm treatment
NCT ID NCT05116384
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether adding a kidney nerve-zapping procedure (renal artery denervation) to the standard heart ablation procedure can better control persistent atrial fibrillation (AF). About 50 adults with persistent AF and controlled or no high blood pressure will be randomly assigned to receive either standard ablation alone or ablation plus the kidney procedure. The main goal is to see if the combination reduces the total time spent in AF over the long term, measured by a heart monitor.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- renal artery denervation (a procedure using radiofrequency energy to disrupt nerves in the kidney arteries) plus catheter ablation (using cryo energy to isolate pulmonary veins)
- What this could lead to
- If successful, this combination procedure could reduce the amount of time people with persistent atrial fibrillation spend in an irregular heart rhythm, potentially improving long-term outcomes.
- What could go wrong
- This is a small pilot study with only 50 participants, so results may not apply to everyone. The added procedure carries risks like blood vessel damage, and it is unclear if the benefit outweighs those risks.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
University of Rochester
RECRUITINGShort Hills, New Jersey, 07078, United States
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