Heart procedure may fix leaky valves in AF patients, new trial aims to prove it

NCT ID NCT06883864

Recruiting now Disease control Sponsor: Beijing Anzhen Hospital Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a catheter ablation procedure can reduce severe mitral valve leakage in people with persistent atrial fibrillation (a type of irregular heartbeat). About 146 adults aged 18-80 with both conditions will either get the ablation plus standard care or just standard care. The main goal is to see if the valve leakage improves after 3 months.

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Conditions

The condition(s) this trial relates to.

atrial fibrillation mitral valve insufficiency persistent atrial fibrillation

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ATRIAL FIBRILLATION (AF) ATRIAL FUNCTIONAL MITRAL REGURGITATION CATHETER ABLATION

Contacts and locations

Locations

Beijing Anzhen Hospital, Capital Medical University
RECRUITING

Beijing, Beijing Municipality, 100029, China
Guangdong Provincial People's Hospital
NOT_YET_RECRUITING

Guangzhou, Guangdong, 510000, China
Peking University Third Hospital
RECRUITING

Beijing, Beijing Municipality, 100191, China
People's Hospital of Ningxia Hui Autonomous Region
RECRUITING

Yinchuan, Ningxia, 750002, China
Shandong Provincial Qianfoshan Hospital
RECRUITING

Jinan, Shandong, 250000, China
Sir Run Run Shaw Hospital, Zhejiang University School of Medicine
RECRUITING

Hangzhou, Zhejiang, 310009, China
Tangdu Hospital-Air Force Medical University
RECRUITING

Xi’an, Shanxi, 710000, China
The First Affiliated Hospital of Anhui Medical University
RECRUITING

Hefei, Anhui, 230022, China
The First Affiliated Hospital of Harbin Medical University
RECRUITING

Harbin, Heilongjiang, 150001, China
The First Affiliated Hospital of Xi'an Jiaotong University
NOT_YET_RECRUITING

Xi’an, Shanxi, 710061, China
The First Affiliated Hospital of Zhengzhou University
NOT_YET_RECRUITING

Zhengzhou, Henan, 450052, China
The Second Affiliated Hospital of Harbin Medical University
RECRUITING

Harbin, Heilongjiang, 450052, China
The Second Hospital of Hebeimedical University
RECRUITING

Shijiazhuang, Hebei, 050000, China
The first hospital of Jilin University
NOT_YET_RECRUITING

Changchun, Jilin, 130000, China
Tongji Hospital Affiliated to Tongji Medical College of Huazhong University of Science and Technology
RECRUITING

Wuhan, Hubei, 430030, China
Wuhan Asia Heart Hospital
RECRUITING

Wuhan, Hubei, 430022, China
Xiamen University Affiliated Cardiovascular Hospital
NOT_YET_RECRUITING

Xiamen, Fujian, 361006, China

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