Can a lower drug dose keep your heart beating steady with fewer side effects?

NCT ID NCT07273994

Recruiting now Disease control Sponsor: Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether a lower daily dose of the heart medication amiodarone can keep the heart in a normal rhythm as well as the standard dose, but with fewer side effects. About 312 adults with persistent atrial fibrillation who have had a successful electrical shock to restore normal rhythm will take part. After one month on the standard dose, half will switch to a lower dose, and both groups will be followed for a year to compare how well the rhythm is maintained and any side effects.

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Conditions

The condition(s) this trial relates to.

atrial fibrillation persistent atrial fibrillation

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PERSISTENT ATRIAL FIBRILLATION

Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

Hospital de la Santa Creu i Sant Pau
RECRUITING

Barcelona, 08025, Spain

Contact Phone: •••-•••-•••• Email: •••••@•••••