New mapping tech could make heart ablation more precise

NCT ID NCT07320560

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This pilot study tests whether a non-invasive global mapping system can help doctors personalize catheter ablation for people with persistent atrial fibrillation (AF). The standard approach isolates the pulmonary veins, but this study adds up to three extra targets based on where the heart shows stable high-rate activity. Researchers will compare outcomes with historical data to see if the personalized approach improves AF termination and reduces recurrence. Forty-five participants will be followed for two years.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

catheter ablation guided by non-invasive global mapping

What this could lead to

If successful, this approach could make atrial fibrillation ablation more effective by targeting the specific sources of the arrhythmia in each patient.

What could go wrong

This is a small pilot study with only 45 participants, so results may not apply to everyone. The procedure still carries standard risks of catheter ablation, such as bleeding or heart damage.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

atrial fibrillation persistent atrial fibrillation

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Central Lisbon University Hospital Centre (CHULC), Hospital de Santa Marta

    NOT_YET_RECRUITING

    Lisbon, 1169-024, Portugal

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Frankfurt University Heart and Vascular Center

    NOT_YET_RECRUITING

    Frankfurt am Main, 60598, Germany

    Contact Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • German Heart Center of the Charité, Charité University Hospital Berlin

    RECRUITING

    Berlin, 10117, Germany

    Contact Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Gregorio Marañón General University Hospital

    NOT_YET_RECRUITING

    Madrid, 28007, Spain

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Hospital Clinic, University of Barcelona

    NOT_YET_RECRUITING

    Barcelona, 08036, Spain

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••