New Dual-Action heart procedure could tame stubborn AFib

NCT ID NCT06165510

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a new two-step procedure for people with long-standing persistent atrial fibrillation (AFib), a type of irregular heartbeat. The procedure combines a minimally invasive surgery on the outside of the heart with a standard catheter ablation inside the heart. Researchers want to see if this approach is safe and works better than standard ablation alone. The trial will enroll 48 adults with persistent AFib for over a year and follow them for 12 months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Convergent ablation procedure using AtriCure EPi-Sense-AF system and LARIAT device

What this could lead to

If successful, this could offer a more effective treatment option for people with long-standing persistent atrial fibrillation, potentially reducing the need for repeat procedures.

What could go wrong

This is a small early feasibility trial with only 48 participants, so results may not apply to everyone. The procedure is more invasive than standard ablation and carries risks like bleeding, infection, or heart complications.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Arrhythmias, Cardiac atrial fibrillation persistent atrial fibrillation

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • St Bartholomew's Hospital

    RECRUITING

    London, EC1A 4AS, United Kingdom

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact