Barts & The London Nhs Trust

This study is testing a new way to place and program a spinal cord stimulator for people with chronic back pain. Doctors will use real-time measurements of nerve activity during surgery to help position the device more precisely. The goal is to see if this method leads to better …

This study aims to improve a common heart procedure called catheter ablation for people with persistent atrial fibrillation (AFib). Researchers will create detailed 3D maps of the heart's electrical activity and scar tissue during the procedure to better understand why AFib retur…

This study compares two common treatments for persistent atrial fibrillation (AF), an irregular heart rhythm. Researchers want to see if catheter ablation (a procedure that scars heart tissue to block faulty electrical signals) works better than electrical cardioversion (a contro…

This study is testing whether using a patient's own bone marrow stem cells can help people with severe, untreatable chest pain (refractory angina). About 110 participants will be randomly assigned to receive either the real stem cell treatment or a 'sham' placebo procedure, and n…

This study aims to understand why some patients survive cardiogenic shock while others don't, by examining their genetic and immune system responses. Researchers will collect blood samples from 300 patients experiencing this life-threatening heart condition across European hospit…

This study aims to understand how a patient's nutritional status and body composition affect their treatment outcomes for Crohn's disease and ulcerative colitis. Researchers will observe 300 patients starting new medications or having surgery, measuring things like muscle mass an…

This study aims to collect heart scan data to train a computer program to predict how well a new heart valve will work after a minimally invasive replacement procedure. Researchers will enroll 40 patients with severe aortic stenosis who are getting a TAVI valve, asking them to ha…

This study aims to understand how quickly patients in intensive care lose muscle in their mouth and throat, and if this causes dangerous swallowing problems. Researchers will measure muscle size and swallowing ability in 160 critically ill patients and compare them to less ill pa…

This study aims to understand why some patients develop severe muscle weakness after surviving a life-threatening heart or lung failure that required advanced life support (ECMO) in the intensive care unit. Researchers will observe 100 adult patients to see how their muscle size,…

This study aims to find out if asking patients more often about their quality of life gives a better picture of the benefits of a heart procedure called catheter ablation. It will compare this procedure to standard medication in 70 adults who have a defibrillator and a dangerous …