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New study aims to uncover why some ICU patients struggle to regain strength

NCT ID NCT03753412

Recruiting now Knowledge-focused Sponsor: Barts & The London NHS Trust Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study follows 100 adults who needed ECMO support for severe heart or lung failure. Researchers will track muscle size, strength, and quality of life over time to understand why some patients develop lasting weakness. No new treatments are being tested; the goal is to gather information that could guide future care.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this study could reveal key factors that help or hinder recovery from ICU-related muscle weakness after severe heart or lung failure.

What could go wrong

This is a small, early observational study with no intervention. It will not directly improve patient outcomes and may not lead to new treatments.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

acute quadriplegic myopathy acute respiratory distress syndrome adult acute respiratory distress syndrome critical illness polyneuropathy heart failure muscle tissue disorder respiratory failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ACUTE RESPIRATORY DISTRESS SYNDROME CARDIAC FAILURE CRITICAL ILLNESS MYOPATHY INTENSIVE CARE (ICU) MYOPATHY INTENSIVE CARE NEUROPATHY INTENSIVE CARE UNIT SYNDROME RESPIRATORY FAILURE

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • St Bartholomew's hospital (Barts NHS trust)

    RECRUITING

    London, EC1A 7BE, United Kingdom

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••