Barts & The London Nhs Trust

This study tested whether adding a drug called paricalcitol (similar to vitamin D) to standard chemotherapy could help people with advanced pancreatic cancer that had stopped responding to initial treatment. 27 adults with metastatic pancreatic cancer took part. The goal was to s…

This study tested a steroid called triamcinolone, given as a shot, in 55 men with castration resistant prostate cancer (cancer that no longer responds to standard hormone therapy). The goal was to see if it could control the cancer longer than current steroid pills, which typical…

This study tested a device called Reactiv8 that stimulates back muscles to relieve chronic low back pain. Twenty adults with long-lasting pain received the implant. Researchers measured changes in pain, disability, sleep, and brain activity to see if the device helps improve dail…

This study compared two methods—CoolStick and ethyl chloride spray—for checking how well the anesthesia is working before a C-section. 64 pregnant women having planned C-sections took part. The goal was to see which tool better measures numbness to light touch and cold. This rese…

This completed study looked at how occipital nerve stimulation (ONS) changes pain perception in people with chronic migraine or cluster headache. Six participants had sensory tests and filled out questionnaires before and after ONS insertion. The goal was to understand pain marke…

This study created a new questionnaire called AF-PROMS to measure how atrial fibrillation (AF) affects a person's quality of life. Researchers worked with 206 adults who have AF to develop and test the scale. The goal was to better understand the day-to-day impact of AF, not to t…

This study looked at how heart surgery impacts the mental health, well-being, and quality of life of adults with Marfan syndrome. Researchers asked 28 participants to fill out questionnaires before surgery and at several points after. The goal is to better understand these effect…

This pilot study looked at whether a larger trial is possible to compare two types of implantable defibrillators (under-the-skin vs traditional wire) in 5 people with hypertrophic cardiomyopathy who need a defibrillator but not a pacemaker. The main goals were to see how many peo…

This study looked at whether giving a special nutritional drink to people who just had an ischemic stroke is practical and helpful. 24 adults took part, with some getting the drink plus standard care and others just standard care. The main goal was to see if a larger study could …