Barts & The London Nhs Trust

This study tested if adding a drug called paricalcitol (a form of vitamin D) to standard chemotherapy could help control advanced pancreatic cancer that had spread. It involved 27 adults whose cancer had not been treated before. The goal was to see if the vitamin D drug could slo…

This small pilot study aimed to see if a larger trial is possible to compare two types of life-saving heart defibrillators. It involved 5 patients with a thickened heart muscle condition (hypertrophic cardiomyopathy) who needed a defibrillator but not a pacemaker. The goal was to…

This study tested whether a steroid drug called triamcinolone, given as a monthly muscle injection alongside standard hormone therapy, could help control advanced prostate cancer that had stopped responding to initial treatments. It involved 55 men, mostly over 70, with the goal …

This small pilot study tested whether adding a daily nutritional supplement drink to standard stroke care is practical and acceptable for patients. It involved 24 adults who had recently suffered an ischemic stroke. The main goal was to see if patients could stick to the regimen …

This study compared two tools doctors use to check if a patient is numb enough before a planned C-section. Researchers tested a reusable metal CoolStick against the standard ethyl chloride spray on 64 patients. The goal was to see if the CoolStick works just as well for checking …

This study aimed to understand how an implanted device that stimulates back muscles works to relieve chronic low back pain. Researchers used special brain and muscle scans (PET/CT) on 20 patients who had the device implanted. The goal was to see what physical changes in the brain…

This small study aimed to understand how a nerve stimulation device might change the way people with severe chronic migraines or cluster headaches feel pain. Researchers compared six patients getting the device to people having other surgeries and healthy volunteers. They used pa…

This study aimed to understand how heart surgery affects the mental health and daily life of adults with Marfan syndrome. Researchers followed 28 patients from three UK hospitals, asking them to complete surveys about their mood, energy, and quality of life before and for a year …