Tailored heart procedure aims to beat atrial fibrillation

NCT ID NCT05633303

Recruiting now Disease control Sponsor: Barts & The London NHS Trust Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a personalized approach to catheter ablation for persistent atrial fibrillation (AF), a common heart rhythm disorder. Researchers will identify specific areas in the heart that drive AF and target them with ablation, aiming to improve success rates. The trial involves 160 participants and will compare outcomes over 12 months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: catheter ablation guided by rate-dependent conduction velocity (RDCV) slowing sites
What this could lead to: If successful, this could lead to more effective, personalized ablation procedures for persistent atrial fibrillation, reducing recurrence and improving patient outcomes.
What could go wrong: This is an early-stage study with 160 participants, so results may not apply to all patients. The approach is complex and may not improve success rates significantly.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

atrial fibrillation persistent atrial fibrillation

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ATRIUM; FIBRILLATION

Contacts and locations

Locations

Barts Heart Centre, Barts Health NHS trust
RECRUITING

London, EC1A 7BE, United Kingdom

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