Could your own bone marrow ease incurable chest pain?
NCT ID NCT05711849
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether a single infusion of a patient's own bone marrow stem cells can reduce chest pain and improve quality of life for people with refractory angina—a severe form of chest pain that doesn't respond to standard treatments. About 110 participants will be randomly assigned to receive either the real stem cell treatment or a sham procedure, and neither they nor their doctors will know which they got. The main goal is to see if angina symptoms improve over six months.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
autologous bone marrow stem cells
What this could lead to
If it works, this could offer a new way to reduce chest pain and improve daily life for people with refractory angina who have few other options.
What could go wrong
This is a mid-stage trial with only 110 participants, so results may not apply to everyone. The procedure involves bone marrow collection and heart artery infusion, which carry risks like bleeding or infection.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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St Bartholomew's Hospital
RECRUITINGLondon, England, EC1A 7BE, United Kingdom
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••