Could your own stem cells ease incurable chest pain?
NCT ID NCT03455725
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This trial tests whether injecting a patient's own bone marrow stem cells into the heart can improve exercise ability and reduce chest pain in people with severe, untreatable angina. About 343 participants will either receive the stem cell treatment or a sham procedure. The goal is to see if this approach offers a new option for those who have not responded to standard therapies.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
patient's own bone marrow stem cells
What this could lead to
If it works, this could offer a new treatment option for people with severe chest pain who have run out of standard options.
What could go wrong
This is a mid-stage trial, so results may not confirm benefit. The procedure involves heart injections, which carry risks like bleeding or heart damage.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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University of Florida
Gainesville, Florida, 32610, United States
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University of Wisconsin Madison
Madison, Wisconsin, 53792, United States