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One procedure to fix rhythm and block clots: new study tests dual approach for AFib

NCT ID NCT07523620

Recruiting now Disease control Sponsor: Abbott Medical Devices Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 14, 2026 · Updated 2 times

Summary

This study tests doing two procedures at once for people with atrial fibrillation (AFib): a catheter ablation to restore normal heart rhythm and a device implant to close off a part of the heart where clots form. The goal is to see if this combined approach is safe and effective at controlling AFib and reducing stroke risk. About 240 adults with AFib and a high stroke risk will take part, and they will stop blood thinners about 3 months after the procedure.

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Conditions

The condition(s) this trial relates to.

atrial fibrillation paroxysmal atrial fibrillation persistent atrial fibrillation

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ATRIAL FIBRILLATION (AF) PAROXYSMAL AF PERSISTENT ATRIAL FIBRILLATION

Contacts and locations

Locations

  • ASST Grande Ospedale Metropolitano

    RECRUITING

    Milan, Lombard, 20162, Italy

  • Cardioangiologisches Centrum am Bethanien Krankenhaus

    RECRUITING

    Frankfurt am Main, Hesse, 60389, Germany

  • Centralny Szpital Kliniczny Uniwersytetu

    NOT_YET_RECRUITING

    Lodz, Poland

  • Centro Cardiologico Monzino

    RECRUITING

    Milan, Italy, 20138, Italy

  • Clinica Universidad de Navarra

    RECRUITING

    Pamplona, Navarre, 31008, Spain

  • Deutsches Herzzentrum der Charite

    RECRUITING

    Berlin, State of Berlin, 13353, Germany

  • Hospital de la Santa Creu I Sant Pau

    RECRUITING

    Barcelona, Catalon, 08025, Spain

  • John Radcliffe Hospital

    NOT_YET_RECRUITING

    Oxford, United Kingdom

  • Mater Private Hospital

    RECRUITING

    Dublin, Dublin, Dublin 7, Ireland

  • Motol and Homolka University Hospital

    RECRUITING

    Prague, Czech Republic, 1500, Czechia

  • Rigshospitalet

    RECRUITING

    Copenhagen, Copenha, 2100, Denmark

  • Royal Sussex County Hospital

    NOT_YET_RECRUITING

    Brighton, United Kingdom

  • Slaskie Centrum Chorob Serca

    NOT_YET_RECRUITING

    Zabrze, Silesian Voivodeship, 41-800, Poland

  • UZ Brussel

    RECRUITING

    Brussels, B CAP R, 1090, Belgium

  • Universitätsklinikum Schleswig-Holstein - Campus Lübeck

    RECRUITING

    Lübeck, Schlesw, 23538, Germany

  • Vilnius University Hospital Santaros Klinikos

    RECRUITING

    Vilnius, Dzukija, 08406, Lithuania

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