One procedure to fix rhythm and block clots: new study tests dual approach for AFib

NCT ID NCT07523620

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests doing two procedures at once for people with atrial fibrillation (AFib): a catheter ablation to restore normal heart rhythm and a device implant to close off a part of the heart where clots form. The goal is to see if this combined approach is safe and effective at controlling AFib and reducing stroke risk. About 240 adults with AFib and a high stroke risk will take part, and they will stop blood thinners about 3 months after the procedure.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

atrial fibrillation paroxysmal atrial fibrillation persistent atrial fibrillation

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • ASST Grande Ospedale Metropolitano

    NOT_YET_RECRUITING

    Milan, Lombard, 20162, Italy

  • Cardioangiologisches Centrum am Bethanien Krankenhaus

    NOT_YET_RECRUITING

    Frankfurt am Main, Hesse, 60389, Germany

  • Centro Cardiologico Monzino

    RECRUITING

    Milan, Italy, 20138, Italy

  • Clinica Universidad de Navarra

    NOT_YET_RECRUITING

    Pamplona, Navarre, 31008, Spain

  • Deutsches Herzzentrum der Charite

    NOT_YET_RECRUITING

    Berlin, State of Berlin, 13353, Germany

  • Hospital de la Santa Creu I Sant Pau

    NOT_YET_RECRUITING

    Barcelona, Catalon, 08025, Spain

  • Mater Private Hospital

    NOT_YET_RECRUITING

    Dublin, Dublin, Dublin 7, Ireland

  • Motol and Homolka University Hospital

    RECRUITING

    Prague, Czech Republic, 1500, Czechia

  • Rigshospitalet

    NOT_YET_RECRUITING

    Copenhagen, Copenha, 2100, Denmark

  • Slaskie Centrum Chorob Serca

    NOT_YET_RECRUITING

    Zabrze, Silesian Voivodeship, 41-800, Poland

  • UZ Brussel

    NOT_YET_RECRUITING

    Brussels, B CAP R, 1090, Belgium

  • Universitätsklinikum Schleswig-Holstein - Campus Lübeck

    NOT_YET_RECRUITING

    Lübeck, Schlesw, 23538, Germany

  • Vilnius University Hospital Santaros Klinikos

    NOT_YET_RECRUITING

    Vilnius, Dzukija, 08406, Lithuania