TYPE 1 DIABETES

This study tested a connected insulin management platform in 36 people with type 1 or type 2 diabetes who use insulin. The goal was to see if the platform helped them take their insulin doses on time and keep their blood sugar in a healthy range. Participants used a continuous gl…

This study looked at whether a type 2 diabetes medicine (SGLT2 inhibitor) can slow kidney disease in teenagers with type 1 diabetes. 86 teens aged 10-18 with early kidney problems took part. Researchers measured changes in urine protein and blood sugar control after 6 months to s…

This study tested the safety of the MiniMed 780G insulin pump paired with the DS5 continuous glucose monitor in 56 children aged 2-6 with type 1 diabetes. The children used the system at home, and researchers tracked how often their blood sugar stayed in a healthy range, as well …

This study tested whether an automated insulin delivery (AID) system works better than standard insulin shots for managing blood sugar in hospitalized adults with type 1 or type 2 diabetes. 130 patients on general medical or surgical floors were randomly assigned to use either th…

This study tested a procedure to transplant insulin-producing cells (islets) into 14 people with type 1 diabetes who had already received a kidney transplant. The goal was to help them stop taking insulin and keep their blood sugar under control. Participants continued taking imm…

This study tested whether shared medical appointments (group visits) could help underserved children aged 8 to 12 with poorly controlled type 1 diabetes. Over 12 months, 14 children and their caregivers attended group visits every 3 months to improve technology use, blood sugar c…

This study looked at whether giving insulin over a longer period (extended bolus) helps control blood sugar after high-fat, high-protein meals in teens with type 1 diabetes. Thirty teens aged 13-19 who already use a closed-loop insulin system took part. The goal was to see if thi…

This pilot study tested a program called FAM for adults with type 1 diabetes who are at risk for diabetic ketoacidosis (DKA). The program involved sharing real-time glucose data with a family member or friend (the "Follower") and giving personalized diabetes education to both the…

This study tested a new automated system that delivers both insulin and pramlintide to manage blood sugar in people with type 1 diabetes. Pramlintide slows digestion to prevent high blood sugar after meals. The system used a continuous glucose monitor to automatically control two…

This study tested a mobile app that gives children and teens with type 1 diabetes personalized strength exercises. Over 24 weeks, researchers checked if the app helped lower daily insulin needs and improve blood sugar control. About 62 participants aged 8-18 took part, all at lea…

This study tested whether the Omnipod 5 system, which automatically adjusts insulin, works better than standard insulin pumps for adults with type 1 diabetes. 196 people took part, first using their usual therapy for 14 days, then either switching to Omnipod 5 or staying on their…

This early-phase study tested whether transplanting insulin-making cells (pancreatic islets) together with a parathyroid gland into the muscle could help people with type 1 diabetes stop using insulin. Only 4 participants who already had a kidney or liver transplant took part. Th…

This study looked at whether taking omega-3 fatty acid supplements can help keep the small blood vessels in the eyes healthy for adults with type 1 diabetes. A total of 82 participants took daily omega-3 supplements and had regular eye exams to check for changes. The goal was to …

This study looked at how well closed-loop insulin pumps (sometimes called artificial pancreas systems) control blood sugar in people with type 1 diabetes during everyday life. Researchers tracked 410 patients from hospital diabetes clinics to see if these devices improved long-te…

This study tested a new feature for an automated insulin pump (closed-loop system) in 15 adults with type 1 diabetes. The feature gives a small priming dose of insulin before meals to improve blood sugar control. Researchers measured how well it kept blood sugar in a healthy rang…

This study looked at two fast-acting insulins, Fiasp and NovoRapid, used in insulin pumps by 44 children and teens with type 1 diabetes. Researchers measured blood sugar levels after meals to see which insulin worked better. The goal was to find the best option for managing diabe…

This study looked at how well an artificial pancreas system helps control blood sugar in teenagers with Type 1 Diabetes during puberty. Over two years, 42 teens used either the artificial pancreas or standard care with a continuous glucose monitor. The goal was to see if the syst…

This study tested a new self-learning bolus calculator that simplifies meal announcements for adolescents and young adults with type 1 diabetes who use automated insulin delivery. Two participants used the system during a hotel stay and at home to see if it was safe and helped ke…

This study tested two versions of an artificial pancreas in 15 adults with type 1 diabetes. One version gave automatic rescue carbs, the other gave both insulin and glucagon. The goal was to see which system better prevented low blood sugar during unannounced exercise and after m…

This study tested an AI-driven artificial pancreas system in 33 young children (ages 2-6) with type 1 diabetes. The system combined an insulin pump with a continuous glucose monitor and automatically adjusted insulin doses using smart algorithms. Over eight weeks at home, researc…

This study tested a faster-acting insulin (Lyumjev) in an artificial pancreas system for people with type 1 diabetes. Twelve adults who already used the artificial pancreas took part. The goal was to see if the new insulin kept blood sugar in a healthy range better than the stand…

This study tested whether regular phone calls and monthly visits with a nurse could help teenagers with type 1 diabetes feel more in control and improve their blood sugar levels. 77 teens aged 13-18 with poorly controlled diabetes took part. The nurse counseling group received ex…

This study tested a new insulin called THDB0206 against a standard insulin (lispro) in 550 Chinese adults with type 1 diabetes. Both groups also used a long-acting insulin (glargine). The main goal was to see how well the new insulin controls blood sugar over 26 weeks. Participan…

This study looked at whether a carbohydrate-restricted diet could improve blood sugar and metabolic control in children and adolescents with type 1 diabetes. Twenty-five participants aged 10-18 followed the diet for a short period. The main goal was to see if it lowered blood glu…

This study tested whether taking oral glucose at a slightly higher blood sugar threshold could prevent mild-to-moderate low blood sugar (hypoglycemia) in adults with type 1 diabetes. Thirty participants used continuous glucose monitors to compare the standard approach with a proa…

This study tested a stem cell treatment called PROCHYMAL in 63 people recently diagnosed with type 1 diabetes. The goal was to see if the treatment could safely help the body keep making some of its own insulin, reducing the need for injected insulin. Participants received multip…

This study tested whether a stronger version of insulin lispro (200 units per mL) works the same as the standard version (100 units per mL) in people with type 1 diabetes. Ninety adults received a single dose of each insulin in random order, and researchers measured how the body …

This study tested whether combining two immune therapies—abatacept (injected weekly) and nasal insulin (sprayed daily then twice weekly)—can help preserve the pancreas's ability to make insulin in people recently diagnosed with type 1 diabetes. 68 participants aged 6 to 21 took p…

This study tested a once-weekly medicine called semaglutide in 115 adults with type 1 diabetes and obesity who already use an automated insulin pump. The goal was to see if adding semaglutide helps improve blood sugar control and reduce weight. Participants received either semagl…

This study tested whether trained peer mentors (ages 20-35) could help young adults (ages 17-25) with type 1 diabetes manage their blood sugar and successfully transition from pediatric to adult care. 144 participants were randomly assigned to receive peer support or standard car…

This study tested whether a newer insulin (glargine) is safer and better at controlling blood sugar than standard human insulin in 400 youth aged 7-25 with type 1 diabetes living in low-resource settings. Participants used continuous glucose monitors to track their levels over 6-…

This study tested whether eccentric training (a type of muscle-lengthening exercise) done in low-oxygen conditions or with creatine supplements can improve blood sugar control, muscle strength, and fitness in adults with type 1 diabetes. Twenty-eight participants completed the pr…

This study tested whether using a more advanced insulin pump with tighter glucose targets helps adults with type 1 diabetes and poor blood sugar control spend more time in a healthy range. Forty participants switched to the new system, and researchers measured changes in their da…

This early-stage trial tested whether a new drug called R-5280 is safe and tolerable for children aged 11 to 17 who were recently diagnosed with type 1 diabetes. Nine participants took the drug or a placebo, and researchers monitored side effects and blood sugar levels over 12 we…

This study tested a new insulin patch pump system in 161 adults with type 1 or type 2 diabetes who needed intensive insulin therapy. Participants were randomly assigned to use either the new patch pump or a standard insulin pump for 7 days in a hospital. The main goal was to see …

This study tested a program where community health workers helped young adults (ages 18-35) from underrepresented minority groups with type 1 diabetes start and continue using diabetes technology like continuous glucose monitors and insulin pumps. Over 9 months, 119 participants …

This study tested whether sending supportive text messages to teenagers with poorly controlled type 1 diabetes could help lower their blood sugar levels (HbA1c). About 92 teens aged 12-21 with high HbA1c took part. The approach used regular SMS reminders and tips, aiming to impro…

This study compared time-restricted eating (eating only during a 6-8 hour window each day) to daily calorie restriction for weight loss and blood sugar control in 32 adults with type 1 diabetes and obesity. Participants followed their assigned diet while continuing insulin and gl…

This study tested a new artificial pancreas system that automatically detects and delivers insulin for missed meals in people with type 1 diabetes. 29 adults used the new system or their usual pump for comparison. The goal was to see if the new algorithm keeps blood sugar in a he…

This study tested whether a faster-acting insulin (Lyumjev) works better than standard insulins (Humalog or Novolog) in an automated insulin pump system for teens with type 1 diabetes. Eleven adolescents aged 12 to 22 took part. Researchers used a special conversion factor to set…

This study tested whether giving teens with type 1 diabetes small rewards and reminders could help them take their insulin more consistently. 173 teens aged 11-17 who used insulin pumps and had trouble with mealtime insulin took part. The goal was to see if this approach could im…

This study tested whether giving a daily mix of two friendly bacteria (Lactobacillus paracasei and Lactobacillus plantarum) to children who had early signs of autoimmunity could prevent them from developing celiac disease, type 1 diabetes, or thyroid disease. The researchers enro…

This study looked at whether exercising before or after lunch works better to keep blood sugar levels stable in women with type 1 diabetes, both during pregnancy and in those planning pregnancy. Twenty women participated, and researchers measured how much time their blood sugar s…

This study tested whether adding a 12-week home-based high intensity interval training program to standard education about preventing low blood sugar (hypoglycemia) could help adults with type 1 diabetes who have lost the ability to sense low blood sugar. 47 participants were ran…

This study tested three different programs (TunedIn, FixIt, and StreamLine) to help adults with type 1 diabetes reduce diabetes distress—the worry and frustration of managing blood sugar. 296 adults with type 1 diabetes and high blood sugar took part. The goal was to see which pr…

This study tested a smart technology platform with a serious game to help 200 teens with type 1 diabetes improve their emotional well-being and quality of life. The game uses artificial intelligence to personalize challenges and teaches skills like coping and social interaction. …

This study tested a program to help teens and young adults (ages 14-25) with type 1 diabetes reduce diabetes-related stress and improve blood sugar levels. Over 2 years, 217 participants either received the program or standard care. The goal was to see if the program could increa…

This study tested a special educational tool for parents of children under 6 with type 1 diabetes. The goal was to see if the tool helps improve blood sugar control and prevent dangerous events like low blood sugar or ketosis. The study included 24 children and followed them for …

This study tested a mobile app designed to help middle-aged adults with type 1 diabetes exercise more safely and confidently. The app uses data from blood sugar monitors, activity, mood, and sleep to give personalized tips and encouragement. 24 people took part to see if the app …

This study tested whether a serious game (a video game designed for learning) helps children aged 10-17 with newly diagnosed type 1 diabetes reinforce what they learn in standard education. 78 participants played the game or received usual care. The study measured diabetes knowle…

This study looked at how two natural substances—GIP (a gut hormone) and alanine (an amino acid from protein)—work together to trigger glucagon release, which raises blood sugar. Researchers tested 10 people with and without type 1 diabetes to see if combining them boosts glucagon…

This study looked at whether measuring glucagon (a hormone that raises blood sugar) after a meal or an injection could help predict the risk of dangerously low blood sugar (hypoglycemia) in people with type 1 diabetes. Researchers studied 62 adults with type 1 diabetes to see if …

This early-stage study tested whether the antidepressant fluoxetine (Prozac) can improve the body's nervous system response during exercise in people with type 1 diabetes. The goal is to reduce the risk of dangerously low blood sugar that often follows physical activity. The stud…

This study looked at how stress, anxiety, and depression affect daily diabetes management in teens and young adults aged 13-26 with type 1 diabetes. Participants used their smartphones to answer quick surveys multiple times a day while wearing a continuous glucose monitor. The go…

This study looked at 24 people with long-standing type 1 diabetes to see if using an automated insulin delivery system plus a low-carbohydrate diet for 8 months could restore their body's ability to release glucagon during low blood sugar (hypoglycemia). Glucagon is a hormone tha…

This study tested a new way of caring for young adults (ages 18-30) with type 1 or type 2 diabetes as they move from pediatric to adult diabetes clinics. 45 participants were split into two groups: one received the new collaborative care model, the other received usual care. Rese…

This study followed 512 children born to parents with type 1 diabetes to find early warning signs of the disease. Researchers looked at immune cells, gut bacteria, and other factors that might predict if a child will develop type 1 diabetes. No treatments were tested; the goal wa…

This study looked at how blood sugar levels change during exercise in men and women with type 1 diabetes. 18 active adults aged 18-45 who use an insulin pump completed two exercise sessions—one with their usual insulin dose and one with a 50% reduction beforehand. Researchers mea…

This study checked how well children with type 1 diabetes and their brothers or sisters follow required and recommended vaccination schedules. Researchers looked at medical records from 60 children and their siblings at one center in Greece. The goal was simply to measure vaccina…

This study checked if adults with very poorly controlled type 1 diabetes (HbA1c over 11%) would keep using a hybrid closed-loop insulin system. Researchers looked back at 66 patients' records to see how many stuck with the system and how well it worked. The goal was to learn if t…

This study looked at how many adults with type 1 diabetes have post-traumatic stress disorder (PTSD) related to their diagnosis or severe low blood sugar episodes. Nearly 300 adults completed a questionnaire to measure PTSD symptoms. The goal was to understand how often this hidd…

This study tested a digital program that tracks stress and blood sugar patterns in caregivers of children with type 1 diabetes. 30 families used the system for 2 months to see if it was easy to use and helpful. The goal was to learn how daily stress relates to serious glucose eve…

This study looked at whether blocking a hormone called GLP-1 can help people with type 1 diabetes release glucagon, a natural safeguard against low blood sugar. Researchers gave 12 adults with type 1 diabetes a substance to block GLP-1 and measured their glucagon levels during lo…

This study looked for easier ways to measure how many insulin-making beta cells are left in people with type 1 diabetes. Currently, doctors use a long, 3-hour meal test that is not very sensitive. Researchers checked if immune cells in the blood or urine tests could give the same…

This study looked at whether a private online chat group on Discord could help teens with Type 1 Diabetes feel supported and manage their condition better. Ten teens aged 16-19 took part for 3 months. Researchers measured how often they joined chats and events, and asked for thei…

This study tested a program called ONBOARD to help 150 adults aged 18-50 with type 1 diabetes learn to use continuous glucose monitors (CGMs) more effectively. The program focused on overcoming daily barriers and improving readiness for advanced diabetes technology. Researchers m…

This study looked at 825 adults with type 1 diabetes who use an insulin pump to see how many also have obstructive sleep apnea. Sleep apnea is a condition where breathing stops and starts during sleep, and it may be linked to worse diabetes control and complications. The goal was…

This study looked at how type 1 diabetes and long-term blood sugar control (HbA1c) affect the body's ability to deliver and use oxygen during exercise. Researchers compared 79 participants—some with type 1 diabetes and some healthy—to understand why people with diabetes often hav…

This study looked at how well automated insulin delivery systems work in physically active adults with type 1 diabetes during everyday life. 76 participants used either a commercial or a do-it-yourself system for 6 weeks while researchers tracked their blood sugar, physical activ…

This study looked at whether oxytocin, a natural hormone, can improve how the pancreas releases glucagon during low blood sugar (hypoglycemia) in people with type 1 diabetes. Sixteen adults with type 1 diabetes took part. Researchers measured glucagon levels after giving oxytocin…

This study checked if a nutrition knowledge questionnaire works well for Turkish teenagers with type 1 diabetes. About 150 teens took part to see if the test is reliable and valid. The goal is to help future research and improve diabetes care by understanding what teens know abou…

This study looked at whether improving sleep can help young adults (ages 18-26) with type 1 diabetes manage their blood sugar better. 39 participants either received coaching to sleep longer and more regularly or just standard diabetes education. The goal was to see if better sle…