TYPE 1 DIABETES

This study will follow 40 adults with type 1 diabetes who previously used an automated insulin delivery system. Researchers want to see if the system's benefits, like better blood sugar control, last for several years. They will also check if long-term use leads to weight gain.

This study looks at whether starting automated insulin delivery (AID) early in children aged 7–16 with new type 1 diabetes leads to better blood sugar control, less stress for families, fewer long-term complications, and is worth the cost compared to daily injections. About 100 k…

This study tests a next-generation automated insulin delivery system (Omnipod M) in up to 40 adults with type 1 diabetes. The goal is to see if the system safely improves blood sugar control by reducing dangerous lows and highs. Participants will use the device during hotel and o…

This study looks at whether starting an automated insulin delivery (AID) system within two weeks of a type 1 diabetes diagnosis helps young patients manage their blood sugar more easily. Researchers will track how many participants start and continue using the system for a year. …

This early-stage study tests a new drug, IMC-S118AI, in adults with type 1 diabetes who have a specific genetic marker (HLA-A*02:01). The goal is to see if the drug is safe and can help preserve the body's remaining ability to produce insulin. Up to 154 participants will receive …

This study tests whether matching specific drugs to a person's unique type of type 1 diabetes can better protect their heart and kidneys. About 57 adults with type 1 diabetes and early signs of heart or kidney issues will receive targeted treatments. The goal is to slow or preven…

This study tests whether tirzepatide, a weekly medication for type 2 diabetes, can help adults with type 1 diabetes use an automated insulin pump without counting carbohydrates at meals. About 105 participants in Canada and Switzerland will either add tirzepatide to their pump th…

This study tests whether sorafenib, a drug currently used for cancer, can help people with newly diagnosed type 1 diabetes keep making their own insulin. Ten adults aged 18-60 will receive either sorafenib or a placebo for a short time. The goal is to see if the drug protects the…

This study tests whether a special education plan using continuous ketone monitoring can lower the risk of diabetic ketoacidosis (DKA) in people with type 1 diabetes who also take SGLT2 inhibitors. About 75 adults with type 1 diabetes will be enrolled. The study compares the spec…

This study tests whether a program that combines psychological support, diet changes, targeted therapy, and parent counseling can improve behavior and thinking in children with Type-1 diabetes who have hypoglycemia unawareness (not feeling low blood sugar). About 50 children aged…

This study tests a program that delivers fresh produce to the homes of pregnant women with type 1 or 2 diabetes who also struggle to get enough healthy food. Participants will also receive group education on diabetes, nutrition, and cooking, plus ongoing support for other needs. …

This study tests if personalized video consultations can help adults with type 1 diabetes feel more confident and manage blood sugar during exercise. Participants get tailored advice on insulin, nutrition, and glucose monitoring. The goal is to improve exercise habits and glucose…

This study explores whether 8 weekly telehealth music therapy sessions can improve quality of life and reduce depression and anxiety in adults with autoimmune endocrine diseases (like Type 1 diabetes or Hashimoto's) and depression. Ten participants will have video sessions with a…

This study tests a program called REDCHiP for parents of children aged 8 or younger with type 1 diabetes. The goal is to see if the program reduces parents' fear of low blood sugar and diabetes-related distress, and improves children's blood sugar levels. About 44 parents will be…

This study will check how common fatty liver disease and liver scarring are in adults with type 1 diabetes or LADA in Quebec. About 100 participants will have a single visit for a liver scan and other tests. The goal is to find undiagnosed liver problems and see if body weight pl…

This study will follow 1300 women with type 1 diabetes to see if a high risk of preeclampsia in early pregnancy is linked to heart disease and other health problems years later. Researchers will check for plaque in neck arteries, blood sugar control, and heart events. The goal is…

This study looks at whether a new tool can help young adults (ages 18-30) with type 1 diabetes and their doctors work together better to make care plans that fit daily life. Researchers will compare usual doctor visits to visits where the tool is used. Participants will have thei…

This study looks at how insulin affects muscle, blood, and the body in people with type 1 diabetes. Researchers will measure protein changes when insulin is low and blood sugar is high. About 70 adults with type 1 diabetes will take part. No treatment is tested; the goal is to le…

This study looks at how non-nutritive sweeteners (like those in diet drinks) affect the heart and blood vessels of young adults with type 1 diabetes. Twenty people aged 15-24 will drink a sports drink and have their blood vessel function measured. The goal is to understand if the…