TYPE 1 DIABETES

This study tests a program called FAMS that helps young adults (ages 18-24) with type 1 diabetes use their continuous glucose monitor (CGM) more regularly. The program involves support from family or friends to encourage better self-care. Researchers will track how often particip…

This study tests whether giving children (ages 6-17) newly diagnosed with stage 3 type 1 diabetes free healthy foods and intensive nutrition counseling for 12 weeks can help preserve their remaining insulin production and prolong the honeymoon phase. All participants continue sta…

This study looks at how safe and effective the Control-IQ 1.5 system is for children ages 2 to 6 with type 1 diabetes. About 144 kids will use the system for 12 months at home. Researchers will track serious side effects like very low blood sugar and diabetic ketoacidosis, and al…

This early-stage trial tests VX-264, a cell therapy designed to replace the insulin-making cells destroyed in type 1 diabetes. Seven adults with long-standing diabetes will be monitored for safety and for signs that their bodies can produce insulin again. The goal is to see if th…

This pilot study tests whether adding a community health worker to the care team helps children newly diagnosed with type 1 diabetes improve blood sugar control. About 28 children under 17 with government insurance and living near Philadelphia will take part. The study tracks blo…

This study looks at whether remotely monitoring continuous glucose monitor (CGM) data can help children and teens newly diagnosed with type 1 diabetes manage their condition better in the first year. About 100 participants will have their CGM data shared with their care team thro…

This study aimed to test if placing insulin-producing cells into the front of the eye is safe for people with type 1 diabetes. Only 6 participants were planned, all needing lifelong immune-suppressing drugs. The study was withdrawn before starting, so no results are available.

This study tests a program called SHIFT2 that helps teens and young adults with type 1 diabetes prepare to move from pediatric to adult medical care. About 109 participants, aged 16-22, and their caregivers will take part. The goal is to see if the program improves blood sugar co…

This study tests whether a Bluetooth-enabled smart insulin pen (InPen) helps teenagers with type 1 diabetes improve their blood sugar control. The pen simplifies insulin dose calculations and tracks doses to prevent mistakes. The study involves 34 teens aged 13-21 who use multipl…

This study tests a program called FAMS-T1D for young adults aged 18-24 with type 1 diabetes. The program helps them set goals and get support from a friend or family member. Researchers want to see if it improves blood sugar levels, diabetes self-care, and reduces diabetes-relate…

This study looked at whether doing light aerobic exercise five days a week for a year can improve heart rate variability—a sign of heart health—in adults with type 1 diabetes. Thirty-five participants were split into two groups: one exercised regularly, the other less often. Rese…

This study tests a family cooking program called DICE for 32 children aged 8-14 with type 1 diabetes who struggle with blood sugar control. The program teaches families how to cook healthy meals together, aiming to improve blood sugar levels and reduce health gaps. It is designed…

This study tests a weekly medicine called tirzepatide in adults with type 1 diabetes who are also overweight or have obesity. The goal is to see if it helps control blood sugar and reduce weight better than a placebo. About 465 people will take part for around 20 months, and all …

This study tests whether colchicine, a common anti-inflammatory drug, can reduce inflammation and lower the risk of heart disease in people with type 1 diabetes. About 100 adults aged 35-80 with type 1 diabetes will take either colchicine or a placebo daily for 26 weeks, with an …

This study tests whether taking a probiotic supplement can lower inflammation in children and teens recently diagnosed with type 1 diabetes. The goal is to see if changing gut bacteria can slow the disease's progression. About 43 participants aged 5-17 will receive either the pro…

This study tests if tirzepatide, a once-weekly injection, is safe and effective for adults with type 1 diabetes who are overweight or have obesity. About 905 participants will receive either tirzepatide or a placebo for 49 weeks. The main goals are to see if it improves blood sug…

This study tests whether a transition coordinator can help 324 youth (ages 17-18) with type 1 diabetes successfully move from pediatric to adult diabetes care. Participants get extra support before, during, and after the switch. Researchers compare them to a group that didn't hav…

This study tests whether a probiotic called Lactiplantibacillus plantarum 299v can reduce inflammation and help preserve the body's ability to produce insulin in people recently diagnosed with type 1 diabetes. About 60 participants aged 3 to 45 will receive either the probiotic o…

This early-phase study tests a treatment called extracorporeal photopheresis (ECP) in 10 adults with type 1 diabetes. ECP filters and treats a patient's blood with light before returning it, aiming to calm the immune attack on the pancreas. The goal is to see if it can reduce ins…

This study tests a new approach to help Black children and young adults with type 1 diabetes use advanced diabetes tools like continuous glucose monitors and insulin pumps. Participants will use a smartphone app and get support from a community health worker, while their care tea…

This study tests a new program called SPACE that brings together school nurses, parents, and diabetes doctors to help children with type 1 diabetes manage their condition at school. About 30 children will take part to see if this team approach is practical and well-liked. The goa…

This study looks at whether hybrid closed-loop systems (smart insulin pumps) can improve heart and blood vessel health in adults with type 1 diabetes. One hundred participants with poorly controlled diabetes will be assigned to either a smart pump, an added diabetes pill, or inte…

This study tests whether metformin, a common diabetes drug, can slow or prevent calcium buildup in the leg arteries of people with type 1 diabetes. About 230 adults with type 1 diabetes and no serious kidney disease will take either metformin or a placebo for two years. Researche…

This study looks at whether Swedish massage or yoga can help lower blood sugar levels in children aged 6 to 12 with type 1 diabetes. Both techniques are relaxing and may reduce stress, which can help control blood sugar. The study involves 50 children from Cairo who do not have o…

This study looks for new biological markers (biomarkers) in the blood that could help doctors diagnose type 1 diabetes earlier and track how the disease progresses. Researchers are comparing teens newly diagnosed with type 1 diabetes to healthy teens without the condition. The go…

This study tests a targeted screening approach to detect undiagnosed heart failure in 706 adults aged 40+ with type 1 or type 2 diabetes who also have additional heart risk factors. Participants are randomly assigned to receive the screening or usual care, and researchers track h…

This study tests whether having a diabetes coach for 6 months improves quality of life for families of children (16 or younger) newly diagnosed with type 1 diabetes. 60 families will be split into two groups: one gets a coach plus usual care, the other gets usual care only. Resea…

This study tests whether a self-help app called MyDiaMate can reduce diabetes-related distress in adults with type 1 diabetes. About 660 participants from four European countries will use the app or continue their usual care. The goal is to see if the app improves emotional well-…

This study tests a sleep screening and support program for teens with type 1 diabetes. Researchers want to see if doctors can easily use the program during clinic visits. About 50 teens who use a continuous glucose monitor will take part.

This study tests the Happy Bob app, which provides peer support for youth with Type 1 Diabetes. About 80 teens will use the app for 6 months and complete surveys on mood, social support, and diabetes management. The goal is to see if the app is easy to use and improves quality of…

This study aimed to see if a slow-digesting carbohydrate supplement taken before exercise could help teens with type 1 diabetes avoid dangerously low blood sugar after biking. The plan was to have each teen complete two bike challenges, once with the supplement and once without, …

This study looks at why many people with type 1 diabetes still develop kidney disease, even with modern glucose monitors and insulin pumps. Researchers will use kidney biopsies and advanced imaging to find hidden risk factors like insulin resistance and inflammation. The goal is …

This study looks for early signs of type 1 diabetes and celiac disease in 115 children and adults who are at higher risk but may not have easy access to healthcare. Participants provide a blood sample to test for specific autoantibodies. The goal is to improve how we screen for t…

This study is creating a large biobank of 48,000 people with diabetes in Hong Kong. Researchers will collect blood samples and health data to find genetic markers that predict serious complications like kidney failure, heart disease, and stroke. The goal is to improve early detec…

This study looks at how type 1 diabetes changes blood vessel and nerve function during exercise. Researchers will measure blood flow and blood pressure in 72 adults with and without diabetes while they do handgrip exercises. The goal is to better understand the body's responses, …

This study looks at how often nonalcoholic fatty liver disease (NAFLD) and advanced liver scarring occur in adults with type 1 diabetes. About 533 participants from a diabetes clinic will get a quick, painless liver scan and blood tests. The goal is to find those at highest risk …

This study was designed to find out what parents of children aged 8-12 with type 1 diabetes need to better manage the condition using insulin pumps and continuous glucose monitors. The goal was to use that information to create an app to support parents and improve diabetes outco…

This study looks at 90 people with type 1 diabetes who use a MiniMed 780G insulin pump. Researchers want to see how blood sugar levels and diet relate to heart and blood vessel health. The goal is to better understand these connections, not to test a new treatment.

This study tests a special online toolkit designed to help young adults (ages 18-30) with type 1 diabetes manage health insurance and financial stress. About 195 participants across the U.S. will use the toolkit and complete surveys over one year. The goal is to see if the toolki…

This study aimed to see if group nutrition classes focused on carbohydrate counting could improve blood sugar control in people with type 1 diabetes. It planned to enroll adults and parents of children with type 1 diabetes who use insulin pumps or injections and continuous glucos…