Infectious disease
MONDO:0005550A disorder directly resulting from the presence and activity of a microbial, viral, or parasitic agent in humans. It can be transmitted by direct or indirect contact.
Also known as: communicable disease, infection, infectious, infectious disease, infectious diseases and manifestations, infectious disorder, transmissible disease, clinical infection
8205 clinical trials for this condition and its sub-types, 295 tagged with Infectious disease itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Infectious disease
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Viral infectious disease 133 trials · 4,436 incl. sub-types
42 sub-types
- Primary viral infectious disease 0 trials · 4,241 incl. sub-types Sub-types →
- Viral respiratory tract infection 47 trials · 564 incl. sub-types Sub-types →
- Coronavinae infectious disease 134 trials
- Disease arising from reactivation of latent virus 4 trials · 89 incl. sub-types Sub-types →
- Viral infection of central nervous system 3 trials · 58 incl. sub-types Sub-types →
- Viral hemorrhagic fever 10 trials · 51 incl. sub-types Sub-types →
- Arbovirus fever 0 trials · 46 incl. sub-types Sub-types →
- Kaposi's sarcoma 45 trials Sub-types →
- Human T-lymphotropic virus 1 infectious disease 5 trials · 34 incl. sub-types Sub-types →
- Rabies 27 trials
- Common wart 26 trials
- Vaccinia 17 trials
- Virus-associated trichodysplasia spinulosa 10 trials
- Immunodeficiency 32B 9 trials
- Arbovirus infection 8 trials
- Viral eye infection 0 trials · 8 incl. sub-types Sub-types →
- COVID-19–associated multisystem inflammatory syndrome in children 7 trials
- Human infection by orthopoxvirus 5 trials
- Herpangina 3 trials
- Milker's nodule 3 trials
- Human betaherpesvirus 5 infectious disease 2 trials
- Parvoviridae infectious disease 1 trial Sub-types →
- Zika virus congenital syndrome 1 trial
- Molluscum contagiosum 1 trial
- Pharyngoconjunctival fever 1 trial
- Newcastle disease 0 trials
- Reoviridae infectious disease 0 trials
- Whitewater Arroyo hemorrhagic fever 0 trials
- Congenital Epstein-Barr virus infection 0 trials
- Congenital varicella syndrome 0 trials
- Contagious pustular dermatitis 0 trials
- Epidemic pleurodynia 0 trials
- Exanthema subitum 0 trials
- Focal epithelial hyperplasia 0 trials
- Infective dermatitis associated with HTLV-1 0 trials
- Lumpy skin disease 0 trials
- Neurolymphomatosis 0 trials
- Pseudorabies 0 trials
- Viral esophagitis 0 trials
- Viral gastritis 0 trials Sub-types →
- Viral labyrinthitis 0 trials
- Viral myositis 0 trials
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Bacterial infectious disease 96 trials · 2,073 incl. sub-types
52 sub-types
- Primary bacterial infectious disease 0 trials · 590 incl. sub-types Sub-types →
- Mycobacterial infectious disease 23 trials · 360 incl. sub-types Sub-types →
- Gram-negative bacterial infections 33 trials · 300 incl. sub-types Sub-types →
- Commensal bacterial infectious disease 0 trials · 272 incl. sub-types Sub-types →
- Gram-positive bacterial infections 7 trials · 251 incl. sub-types Sub-types →
- Pulpitis 191 trials
- Bacterial infectious disease with sepsis 78 trials · 113 incl. sub-types Sub-types →
- Bacterial sexually transmitted disease 8 trials · 113 incl. sub-types Sub-types →
- Anaerobic bacteria infectious disease 2 trials · 99 incl. sub-types Sub-types →
- Spirochaetales infections 1 trial · 97 incl. sub-types Sub-types →
- Bacterial arthritis 24 trials · 94 incl. sub-types Sub-types →
- Staphylococcal infection 41 trials · 84 incl. sub-types Sub-types →
- Bacterial urinary tract infection 55 trials · 81 incl. sub-types Sub-types →
- Clostridium difficile colitis 69 trials
- Bacterial pneumonia 28 trials · 65 incl. sub-types Sub-types →
- Skin disease caused by bacterial infection 13 trials · 57 incl. sub-types Sub-types →
- Meningococcal infection 47 trials · 55 incl. sub-types Sub-types →
- Bifidobacteriales infectious disease 0 trials · 44 incl. sub-types Sub-types →
- Bacterial meningitis 12 trials · 37 incl. sub-types Sub-types →
- Pseudomonas infection 25 trials · 29 incl. sub-types Sub-types →
- Escherichia coli infection 26 trials Sub-types →
- Vibrio infectious disease 0 trials · 16 incl. sub-types Sub-types →
- Mycoplasmoides infection 7 trials · 15 incl. sub-types Sub-types →
- Bacterial endocarditis 15 trials
- Haemophilus infectious disease 14 trials Sub-types →
- Necrotizing soft tissue infection 13 trials Sub-types →
- Empyema 10 trials · 11 incl. sub-types Sub-types →
- Chorioamnionitis 10 trials
- Klebsiella infectious disease 5 trials · 9 incl. sub-types Sub-types →
- Rickettsiosis 2 trials · 7 incl. sub-types Sub-types →
- Tracheitis 2 trials · 7 incl. sub-types Sub-types →
- Enterococcus infectious disease 1 trial · 4 incl. sub-types Sub-types →
- Yersinia infectious disease 0 trials · 4 incl. sub-types Sub-types →
- Peritonsillar abscess 4 trials
- Bacterial conjunctivitis 3 trials Sub-types →
- Bacterial hemorrhagic fever 0 trials · 3 incl. sub-types Sub-types →
- Bacterial gastritis 2 trials
- Fournier gangrene 2 trials
- Septic peritonitis 2 trials
- Opportunistic bacterial infectious disease 0 trials · 1 incl. sub-types Sub-types →
- Actinobacillus infectious disease 0 trials
- Aeromonas hydrophila infectious disease 0 trials Sub-types →
- Pectobacterium carotovorum infection 0 trials
- Proteus infectious disease 0 trials
- Whipple disease 0 trials
- Bacterial myositis 0 trials Sub-types →
- Botryomycosis 0 trials Sub-types →
- Idiopathic severe pneumococcemia 0 trials
- Noma 0 trials
- Pasteurellosis 0 trials Sub-types →
- Pneumonic pasteurellosis 0 trials
- Rat-bite fever 0 trials Sub-types →
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Sexually transmitted disease 127 trials · 1,703 incl. sub-types
3 sub-types
- Viral sexually transmitted disease 5 trials · 1,589 incl. sub-types Sub-types →
- Bacterial sexually transmitted disease 8 trials · 113 incl. sub-types Sub-types →
- Trichomonas vaginitis urogenital infection 7 trials Sub-types →
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Respiratory tract infectious disorder 174 trials · 1,330 incl. sub-types
14 sub-types
- Pneumonia 326 trials · 610 incl. sub-types Sub-types →
- Viral respiratory tract infection 47 trials · 564 incl. sub-types Sub-types →
- Fungal lung infectious disease 6 trials · 57 incl. sub-types Sub-types →
- Pulmonary non-tuberculous mycobacterial infection 48 trials
- Streptococcal sore throat 8 trials
- Pleural tuberculosis 7 trials Sub-types →
- Tracheitis 2 trials · 7 incl. sub-types Sub-types →
- Lung abscess 3 trials
- Pneumonic plague 3 trials
- Tuberculous fibrosis of lung 3 trials
- Laryngeal diphtheria 0 trials
- Laryngeal tuberculosis 0 trials
- Nasopharyngeal diphtheria 0 trials
- Silicotuberculosis 0 trials
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Digestive system infectious disorder 4 trials · 605 incl. sub-types
22 sub-types
- Viral hepatitis 12 trials · 443 incl. sub-types Sub-types →
- Infectious colitis 0 trials · 69 incl. sub-types Sub-types →
- Intestinal infectious disease 3 trials · 49 incl. sub-types Sub-types →
- Small intestinal bacterial overgrowth 18 trials
- Parasitic intestinal disorder 0 trials · 16 incl. sub-types Sub-types →
- Liver abscess (disease) 4 trials
- Campylobacteriosis 3 trials Sub-types →
- Bacterial gastritis 2 trials
- Gastrointestinal tuberculosis 0 trials · 2 incl. sub-types Sub-types →
- Aeromonas hydrophila intestinal disease 0 trials
- Salmonella gastroenteritis 0 trials
- Whipple disease 0 trials
- Anal verrucous carcinoma 0 trials
- Bacterial esophagitis 0 trials
- Colorectal Kaposi sarcoma 0 trials Sub-types →
- Fungal esophagitis 0 trials Sub-types →
- Fungal gastritis 0 trials
- Internal hirudiniasis 0 trials
- Oropharyngeal anthrax 0 trials
- Polycystic echinococcosis 0 trials
- Viral esophagitis 0 trials
- Viral gastritis 0 trials Sub-types →
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Infectious disease with sepsis 380 trials · 472 incl. sub-types
1 sub-type
- Bacterial infectious disease with sepsis 78 trials · 113 incl. sub-types Sub-types →
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Vector-borne disease 9 trials · 448 incl. sub-types
49 sub-types
- Malaria 134 trials · 169 incl. sub-types Sub-types →
- Dengue disease 74 trials Sub-types →
- Tick-borne infectious disease 9 trials · 41 incl. sub-types Sub-types →
- Chikungunya 31 trials
- Leishmaniasis 8 trials · 27 incl. sub-types Sub-types →
- Mycobacterium avium complex disease 22 trials
- Schistosomiasis 15 trials · 17 incl. sub-types Sub-types →
- Yellow fever 16 trials
- Zika virus infectious disease 15 trials
- Chagas disease 12 trials
- Filarial elephantiasis 9 trials
- Onchocerciasis 9 trials Sub-types →
- Arbovirus infection 8 trials
- Lassa fever 6 trials
- Crimean-Congo hemorrhagic fever 5 trials
- Mosquito-borne viral encephalitis 0 trials · 5 incl. sub-types Sub-types →
- Listeriosis 4 trials Sub-types →
- Plague 2 trials · 4 incl. sub-types Sub-types →
- Q fever 3 trials
- Rift valley fever 3 trials
- Human African trypanosomiasis 2 trials · 3 incl. sub-types Sub-types →
- Typhus 0 trials · 3 incl. sub-types Sub-types →
- Hantavirus hemorrhagic fever with renal syndrome, Puumala virus type 2 trials
- Hantavirus pulmonary syndrome 2 trials
- Relapsing fever 2 trials Sub-types →
- Oropouche fever 1 trial
- Venezuelan equine encephalitis 1 trial
- West Nile fever 1 trial Sub-types →
- Zika virus congenital syndrome 1 trial
- Lymphocytic choriomeningitis 1 trial
- Spotted fever 0 trials · 1 incl. sub-types Sub-types →
- Tungiasis 1 trial
- Alkhurma hemorrhagic fever 0 trials
- Argentine hemorrhagic fever 0 trials
- Bolivian hemorrhagic fever 0 trials
- Colorado tick fever 0 trials
- Hantavirus hemorrhagic fever with renal syndrome, Dobrava-Belgrade virus type 0 trials
- Hantavirus hemorrhagic fever with renal syndrome, Seoul virus type 0 trials
- Murray valley encephalitis 0 trials
- O'nyong'nyong fever 0 trials
- Ross river fever 0 trials
- Venezuelan hemorrhagic fever 0 trials
- Whitewater Arroyo hemorrhagic fever 0 trials
- Bacterial esophagitis 0 trials
- Fungal esophagitis 0 trials Sub-types →
- Phlebotomus fever 0 trials
- Rat-bite fever 0 trials Sub-types →
- Trench fever 0 trials
- Tularemia 0 trials Sub-types →
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Skin disorder caused by infection 3 trials · 349 incl. sub-types
15 sub-types
- Skin infection 12 trials · 152 incl. sub-types Sub-types →
- Herpes zoster 73 trials Sub-types →
- Skin disease caused by bacterial infection 13 trials · 57 incl. sub-types Sub-types →
- Parasitic skin disorder 1 trial · 37 incl. sub-types Sub-types →
- Chickenpox 26 trials
- Common wart 26 trials
- Virus-associated trichodysplasia spinulosa 10 trials
- Plantar wart 9 trials
- Hand, foot and mouth disease 7 trials
- Viral exanthem 0 trials · 3 incl. sub-types Sub-types →
- Epstein-Barr virus hepatitis 0 trials
- Exanthema subitum 0 trials
- Herpetic whitlow 0 trials
- Infective dermatitis associated with HTLV-1 0 trials
- Variola major infectious disease 0 trials
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Parasitic infectious disease 12 trials · 342 incl. sub-types
17 sub-types
- Protozoa infectious disease 3 trials · 241 incl. sub-types Sub-types →
- Helminthiasis 13 trials · 67 incl. sub-types Sub-types →
- Parasitic skin disorder 1 trial · 37 incl. sub-types Sub-types →
- Parasitic eye infection 0 trials · 16 incl. sub-types Sub-types →
- Parasitic intestinal disorder 0 trials · 16 incl. sub-types Sub-types →
- Cryptococcosis 5 trials · 10 incl. sub-types Sub-types →
- Demodicidosis 5 trials · 6 incl. sub-types Sub-types →
- Parasitemia 5 trials
- Coccidioidomycosis 4 trials
- Amoebiasis due to Entamoeba histolytica 1 trial
- Amoebiasis due to free-living amoebae 1 trial
- Strongylida infectious disease 0 trials
- Cutaneous larva migrans 0 trials Sub-types →
- Distomatosis 0 trials
- Microsporidiosis 0 trials Sub-types →
- Parasitic Ichthyosporea infectious disease 0 trials Sub-types →
- Parasitic myositis 0 trials Sub-types →
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Fungal infectious disease 38 trials · 293 incl. sub-types
18 sub-types
- Opportunistic mycosis 0 trials · 147 incl. sub-types Sub-types →
- Cutaneous mycosis 1 trial · 118 incl. sub-types Sub-types →
- Fungal lung infectious disease 6 trials · 57 incl. sub-types Sub-types →
- Systemic mycosis 27 trials · 54 incl. sub-types Sub-types →
- Pneumocystis infectious disease 4 trials · 19 incl. sub-types Sub-types →
- Fungal meningitis 3 trials · 10 incl. sub-types Sub-types →
- Fungal infection of eye 0 trials · 7 incl. sub-types Sub-types →
- Scedosporiosis 2 trials
- Sporotrichosis 1 trial Sub-types →
- Alternariosis 0 trials Sub-types →
- Emergomycosis 0 trials
- Fungal discitis 0 trials
- Fungal esophagitis 0 trials Sub-types →
- Fungal gastritis 0 trials
- Fungal myositis 0 trials
- Invasive scopulariopsis infection 0 trials
- Mycotic endocarditis 0 trials
- Mycotoxicosis 0 trials Sub-types →
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Urinary tract infection 156 trials · 250 incl. sub-types
5 sub-types
- Bacterial urinary tract infection 55 trials · 81 incl. sub-types Sub-types →
- Renal infectious disease 16 trials · 64 incl. sub-types Sub-types →
- Trichomonas vaginitis urogenital infection 7 trials Sub-types →
- Urinary schistosomiasis 3 trials
- Pyoureter 0 trials
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Infectious disorder of the nervous system 4 trials · 231 incl. sub-types
10 sub-types
- Central nervous system infectious disorder 10 trials · 163 incl. sub-types Sub-types →
- Tetanus 43 trials Sub-types →
- Rabies 27 trials
- Tropical spastic paraparesis 3 trials
- Cytomegalovirus retinitis 2 trials
- Tabes dorsalis 2 trials
- Histoplasmosis retinitis 1 trial
- Ophthalmic herpes zoster 0 trials
- Postinfectious cerebellitis 0 trials
- Tick paralysis 0 trials
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Nosocomial infection 115 trials · 116 incl. sub-types
3 sub-types
- Iatrogenic Kaposi's sarcoma 1 trial
- Iatrogenic Creutzfeldt-Jakob disease 0 trials
- Iatrogenic botulism 0 trials
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Infective arthritis 25 trials · 100 incl. sub-types
2 sub-types
- Bacterial arthritis 24 trials · 94 incl. sub-types Sub-types →
- Infectious discitis 4 trials Sub-types →
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Eye infectious disorder 4 trials · 61 incl. sub-types
10 sub-types
- Endophthalmitis 9 trials · 38 incl. sub-types Sub-types →
- Parasitic eye infection 0 trials · 16 incl. sub-types Sub-types →
- Viral eye infection 0 trials · 8 incl. sub-types Sub-types →
- Fungal infection of eye 0 trials · 7 incl. sub-types Sub-types →
- Hordeolum 1 trial · 7 incl. sub-types Sub-types →
- Bacterial conjunctivitis 3 trials Sub-types →
- Infectious panuveitis 1 trial
- Chronic canaliculitis 0 trials
- Infectious scleritis 0 trials
- Ocular tuberculosis 0 trials
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Infective vaginitis 1 trial · 61 incl. sub-types
4 sub-types
- Bacterial vaginosis 44 trials
- Vulvovaginal candidiasis 25 trials
- Trichomonal vulvovaginitis 1 trial
- Herpetic vulvovaginitis 0 trials
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Hemorrhagic fever 4 trials · 54 incl. sub-types
2 sub-types
- Viral hemorrhagic fever 10 trials · 51 incl. sub-types Sub-types →
- Bacterial hemorrhagic fever 0 trials · 3 incl. sub-types Sub-types →
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Infective endocarditis 46 trials · 52 incl. sub-types
3 sub-types
- Bacterial endocarditis 15 trials
- Subacute bacterial endocarditis 4 trials
- Mycotic endocarditis 0 trials
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Prosthesis-related infectious disease 49 trials
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Ear infection 9 trials · 40 incl. sub-types
5 sub-types
- Infectious otitis media 24 trials
- Otitis externa 3 trials · 12 incl. sub-types Sub-types →
- Geniculate herpes zoster 0 trials
- Infectious otitis interna 0 trials
- Viral labyrinthitis 0 trials
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Abscess 9 trials · 33 incl. sub-types
11 sub-types
- Breast abscess 5 trials
- Epidural abscess 5 trials
- Liver abscess (disease) 4 trials
- Peritonsillar abscess 4 trials
- Intracranial abscess 3 trials
- Lung abscess 3 trials
- Corneal abscess 1 trial
- Intersphincteric abscess 0 trials
- Pyoureter 0 trials
- Splenic abscess 0 trials
- Vitreous abscess 0 trials
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Infectious embryofetopathy 2 trials · 25 incl. sub-types
10 sub-types
- Congenital herpes virus infection 0 trials · 15 incl. sub-types Sub-types →
- Congenital syphilis 7 trials Sub-types →
- Congenital toxoplasmosis 2 trials
- Congenital Epstein-Barr virus infection 0 trials
- Congenital enterovirus infection 0 trials
- Congenital rubella syndrome 0 trials
- Congenital varicella syndrome 0 trials
- Fetal enterovirus syndrome 0 trials
- Fetal parainfluenza virus type 3 syndrome 0 trials
- Fetal parvovirus syndrome 0 trials
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Infectious peritonitis 22 trials · 23 incl. sub-types
3 sub-types
- Septic peritonitis 2 trials
- Diphtheritic peritonitis 0 trials
- Tuberculous peritonitis 0 trials
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Nail infection 0 trials · 14 incl. sub-types
3 sub-types
- Tinea unguium 14 trials
- Fungal infection of the toenail 4 trials
- Herpetic whitlow 0 trials
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Coinfection 12 trials
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Hookworm infectious disease 10 trials
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Puerperal infection 9 trials
-
Acanthamoeba infectious disease 0 trials · 5 incl. sub-types
2 sub-types
- Acanthamoeba keratitis 5 trials
- Granulomatous amebic encephalitis 0 trials
-
Epididymitis 2 trials
2 sub-types
- Epididymo-orchitis 0 trials Sub-types →
- Tuberculous epididymitis 0 trials
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Mycetoma 1 trial
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Ciliophora infectious disease 0 trials
1 sub-type
- Balantidiasis 0 trials
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Hirudiniasis 0 trials
2 sub-types
- External hirudiniasis 0 trials
- Internal hirudiniasis 0 trials
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Infectious myositis 0 trials
1 sub-type
- Parasitic myositis 0 trials Sub-types →
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Protothecosis 0 trials
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Pythiosis 0 trials
Most studied deeper sub-types
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Experimental malaria vaccine aims to block parasite growth
Vaccine CompletedThis trial tests an experimental malaria vaccine called RH5.2-VLP, given with an adjuvant (Matrix-M) to boost the immune response. Healthy adults aged 18–45 receive three doses, and some volunteers are later exposed to malaria parasites in a controlled setting to see if the vacci…
Phase 1/2 • Sponsor: University of Oxford • Aim: Vaccine
Last updated Jul 22, 2026 00:00 UTC
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New bird flu booster shot shows promise in early trial
Vaccine CompletedThis study tested a booster vaccine for H5N6 bird flu in about 260 adults. Some had previously received an H5N1 bird flu vaccine, while others had not. The goal was to see if the booster was safe and triggered a strong immune response. Participants received one or two doses of th…
Phase 2 • Sponsor: Seqirus • Aim: Vaccine
Last updated Jun 27, 2026 12:33 UTC
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One vaccine dose enough for COVID survivors? new study investigates
Vaccine CompletedThis study looked at whether people who had COVID-19 more than 5 months ago need only one dose of the Pfizer mRNA vaccine, instead of the usual two. It included 267 healthy adults aged 18-45 or 65 and older, some with prior infection and some without. Researchers measured antibod…
Phase 2 • Sponsor: ANRS, Emerging Infectious Diseases • Aim: Vaccine
Last updated Jun 27, 2026 12:03 UTC
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Cholera vaccine vaxchora put to the test in immune response study
Vaccine CompletedThis phase 2 trial tested the oral cholera vaccine Vaxchora in 34 healthy adults to see how well it triggers protective antibodies and immune cells. Participants received a single dose, and researchers measured antibody levels, B cells, and T cell responses. The goal is to unders…
Phase 2 • Sponsor: Emory University • Aim: Vaccine
Last updated Jun 27, 2026 09:04 UTC
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New combo vaccine for babies shows promise in large trial
Vaccine CompletedThis study tested a new vaccine called BK1310 in 370 healthy infants to see if it safely protects against several serious diseases: Hib, diphtheria, pertussis, tetanus, and polio. The vaccine was compared to existing vaccines. The goal was to check how well the infants' immune sy…
Phase 3 • Sponsor: Tanabe Pharma Corporation • Aim: Vaccine
Last updated Jun 27, 2026 08:08 UTC
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New COVID booster vaccine shows promise in early trial
Vaccine CompletedThis study tested a new COVID-19 booster vaccine called SpiN-Tec in 432 healthy adults aged 18 to 85 who had already received full vaccination and at least one booster. The vaccine was compared to approved boosters like Covishield and Comirnaty. The goal was to check safety and w…
Phase 1/2 • Sponsor: Federal University of Minas Gerais • Aim: Vaccine
Last updated Jun 26, 2026 17:23 UTC
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Could a stem cell drug tame rare immune disease?
Disease control CompletedThis early-phase study tests whether Mozobil, a drug already used to boost stem cells for transplants, can safely raise white blood cell counts in people with WHIMS. WHIMS is a rare genetic condition that traps infection-fighting cells in the bone marrow, leading to frequent infe…
Phase 1/2 • Sponsor: National Institute of Allergy and Infectious Diseases (NIAID) • Aim: Disease control
Last updated Sep 11, 2026 00:00 UTC
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New biopsy technique could slash infection risk in prostate cancer detection
Disease control CompletedThis study compared two ways of taking prostate tissue samples: the standard transrectal method (through the rectum) and a newer transperineal method (through the skin between the scrotum and anus). Over 1,000 men participated to see if the transperineal approach causes fewer inf…
Sponsor: Weill Medical College of Cornell University • Aim: Disease control
Last updated Aug 26, 2026 00:00 UTC
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Rare disease drug shows promise in reducing infections
Disease control CompletedThis study tested two drugs, plerixafor and G-CSF, in 20 people with WHIM syndrome, a rare genetic condition that causes frequent infections and warts. Participants received each drug for a year and tracked their infections. The goal was to see which drug better reduced infection…
Phase 2/3 • Sponsor: National Institute of Allergy and Infectious Diseases (NIAID) • Aim: Disease control
Last updated Jun 28, 2026 00:00 UTC
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Can antibody infusions shield CLL patients from deadly infections?
Disease control CompletedThis study tested whether regular infusions of Panzyga (a concentrated antibody solution from donated blood) could prevent serious infections in people with chronic lymphocytic leukemia (CLL) who also have low antibody levels. The trial included 247 adults with CLL who were recei…
Phase 3 • Sponsor: Octapharma • Aim: Disease control
Last updated Jun 27, 2026 13:03 UTC
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New study tests better ways to link former inmates to HIV and addiction treatment
Disease control CompletedThis study tested two different approaches to help people recently released from jail or prison get connected to care for HIV, hepatitis C, STIs, and opioid use disorder. Over 600 adults took part. The goal was to see which method worked better for starting and staying on treatme…
Sponsor: Yale University • Aim: Disease control
Last updated Jun 27, 2026 13:02 UTC
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Magnetic pulses may tame implant gum infection
Disease control CompletedThis study tested whether pulsed electromagnetic fields (PEMF) can reduce harmful bacteria and improve healing around dental implants. 35 healthy adults with at least two missing teeth took part. Researchers measured changes in bacteria types and gum tissue volume to see if PEMF …
Sponsor: Jamil awad shibli • Aim: Disease control
Last updated Jun 27, 2026 12:28 UTC
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Can a special toothbrush stop pneumonia in ICU patients?
Disease control CompletedThis study tested whether using a suction toothbrush for oral care could reduce ventilator-associated pneumonia (VAP) in intubated ICU patients. 111 adults on breathing machines were randomly assigned to cleaning with distilled water or a chlorhexidine solution using the suction …
Sponsor: Koç University • Aim: Disease control
Last updated Jun 27, 2026 12:23 UTC
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Cat scratch cure? injection may shrink swollen nodes faster
Disease control CompletedThis study tested whether injecting the antibiotic gentamicin directly into swollen lymph nodes helps people with cat scratch disease recover faster. 75 participants received either the injection or a placebo, along with standard oral antibiotics. The goal was to see if the injec…
Phase 3 • Sponsor: University Hospital, Toulouse • Aim: Disease control
Last updated Jun 27, 2026 12:00 UTC
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Vacuum dressing may cut infection risk after emergency abdominal surgery
Disease control CompletedThis study looked at 50 adults who had emergency surgery for a belly infection (peritonitis). It compared a special vacuum dressing (NPWT) with standard wound closure to see which better prevents surgical site infections. The goal was to find a way to help wounds heal faster and …
Sponsor: Medical University of Gdansk • Aim: Disease control
Last updated Jun 27, 2026 08:01 UTC
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Gut bacteria fix for obesity skin woes?
Disease control CompletedThis study tested whether taking a daily probiotic called Bifidobacterium longum for one month could improve skin barrier damage in people with obesity. 140 participants took either the active probiotic or an inactive placebo. The researchers measured skin water loss and checked …
Sponsor: Shenzhen People's Hospital • Aim: Disease control
Last updated Jun 27, 2026 08:01 UTC
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Can a probiotic pill restore vaginal balance? new study explores
Disease control CompletedThis study tested whether an oral probiotic supplement could help restore healthy bacteria in the vagina. It included 32 women aged 35-43 with vaginal imbalance and fertility concerns. Researchers measured how well the probiotic colonized the body and its effects on immune and an…
Sponsor: Fertypharm • Aim: Disease control
Last updated Jun 27, 2026 08:01 UTC
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Can a simple dressing save lives? new trial targets ECMO infections
Disease control CompletedThis study tested whether using a special antiseptic dressing on ECMO tubes can reduce serious infections in critically ill patients. About 270 adults on ECMO for heart or lung failure were randomly assigned to get either the special dressing or a standard one. The goal was to se…
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Disease control
Last updated Jun 27, 2026 07:59 UTC
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Rural patients get Hospital-Level care at home in landmark trial
Disease control CompletedThis study looked at whether giving hospital-level care to acutely ill adults in their own homes in rural areas works well. 160 people with various conditions like infections, heart failure, or COPD took part. The goal was to see if this approach could lower costs and help patien…
Sponsor: Brigham and Women's Hospital • Aim: Disease control
Last updated Jun 27, 2026 07:57 UTC
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Brain surgery infection fighter: vancomycin powder put to the test
Disease control CompletedThis study tested whether applying vancomycin powder directly to the surgical wound during brain surgery can reduce infections. Over 1,100 adults having neurosurgery were randomly assigned to receive either the topical vancomycin or standard care. The main goal was to see if the …
Phase 3 • Sponsor: Columbia University • Aim: Disease control
Last updated Jun 27, 2026 07:55 UTC
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Can a special diet before surgery prevent infections in head and neck cancer patients?
Disease control CompletedThis phase 3 trial tested whether giving a special nutritional supplement (immunonutrition) before and after surgery could reduce infections in 311 patients with head and neck cancer. Participants were randomly assigned to one of three nutrition regimens. The main goal was to see…
Phase 3 • Sponsor: Centre Antoine Lacassagne • Aim: Disease control
Last updated Jun 27, 2026 07:53 UTC
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Could a cold virus drug prevent COPD Flare-Ups?
Disease control CompletedThis study tested whether the drug vapendavir can reduce breathing problems in people with COPD who catch a rhinovirus (common cold). Fifty-two adults with COPD were given either vapendavir or a placebo after being exposed to the virus. The main goal was to see if vapendavir lowe…
Phase 2 • Sponsor: Altesa Biosciences, Inc. • Aim: Disease control
Last updated Jun 27, 2026 07:53 UTC
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Could a mouthwash replace a tube down your throat to diagnose pneumonia?
Diagnosis CompletedThis study tests whether a simple salt-water mouth rinse can detect pneumocystis, a lung infection that can be life-threatening in people with weak immune systems. Current diagnosis requires coughing up sputum or a tube inserted into the lungs, which can be uncomfortable. Researc…
Sponsor: National Institute of Allergy and Infectious Diseases (NIAID) • Aim: Diagnosis
Last updated Sep 18, 2026 00:00 UTC
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A simple blood test may spot severe bacterial infections faster in the ER
Diagnosis CompletedResearchers in Basel are testing whether a blood marker called HNL can help emergency doctors quickly tell whether an infection is bacterial or viral. The study will enroll about 516 adults with suspected infection and signs of physiological disturbance. Doctors will measure HNL …
Sponsor: University Hospital, Basel, Switzerland • Aim: Diagnosis
Last updated Sep 12, 2026 00:00 UTC
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New DNA test could speed up bone infection diagnosis
Diagnosis CompletedThis study looks at whether a new DNA sequencing technology (Nanopore) can better identify infections in broken bones compared to standard lab cultures. Researchers will collect bone samples from 100 adults with fracture-related infections and compare the results from both method…
Sponsor: Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer • Aim: Diagnosis
Last updated Jul 09, 2026 00:00 UTC
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New DNA test could revolutionize diagnosis of eye infections
Diagnosis CompletedThis study tested a new method called metagenomic deep sequencing (MDS) to find the cause of eye infections. 100 adults with suspected infectious uveitis or endophthalmitis were randomly assigned to have their doctors receive MDS results or not, in addition to standard tests. The…
Sponsor: University of California, San Francisco • Aim: Diagnosis
Last updated Jun 28, 2026 00:00 UTC
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Fingerprick test could speed up detection of blood clots and infections
Diagnosis CompletedThis study tested whether a quick fingerstick blood test for D-Dimer (clot marker) and CRP (inflammation marker) gives the same results as standard lab tests using blood from a vein. Researchers enrolled 111 adults and compared results from fingerstick, venous whole blood, and pl…
Sponsor: LumiraDx UK Limited • Aim: Diagnosis
Last updated Jun 27, 2026 14:00 UTC
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New rapid test for infection and inflammation put to the test
Diagnosis CompletedThis study looked at how well a new, quick finger-prick test (LumiraDx CRP) measures CRP levels compared to a standard lab test. CRP is a marker of infection, inflammation, or tissue injury. 79 adults with symptoms of these conditions took part. The goal was to see if the new tes…
Sponsor: LumiraDx UK Limited • Aim: Diagnosis
Last updated Jun 27, 2026 13:07 UTC
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Quick strip test could speed up infection diagnosis in cirrhosis patients
Diagnosis CompletedThis study tested a simple strip test called PeriScreen to quickly diagnose infection in the belly fluid of people with cirrhosis. The goal is to see if the strip can spot infections as accurately as standard lab tests, helping doctors start treatment faster. About 649 adults wit…
Sponsor: Centre Hospitalier Departemental Vendee • Aim: Diagnosis
Last updated Jun 27, 2026 12:29 UTC
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New rapid test could help fight superbugs in veterans
Diagnosis CompletedThis completed study tested a new rapid diagnostic tool to quickly identify antibiotic-resistant bacteria in wounded warriors and veterans. Over 2,200 participants provided samples from blood, lungs, or skin. The goal was to see if the test could accurately detect resistant bacte…
Sponsor: Connie Price • Aim: Diagnosis
Last updated Jun 27, 2026 08:03 UTC
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New PET scan technique aims to sniff out hidden infections
Diagnosis CompletedThis early study tested whether a special PET scan using a radioactive form of vitamin B9 (11C-PABA) can help doctors see infections deep inside the body. Researchers scanned 13 healthy people and patients with known or suspected infections. The goal was to see if this method can…
Sponsor: Johns Hopkins University • Aim: Diagnosis
Last updated Jun 27, 2026 08:03 UTC
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New biosensors aim to diagnose infections in minutes
Diagnosis CompletedThis study tested two new types of biosensor platforms to detect viruses, bacteria, and parasites in blood and respiratory samples. The goal was to see if these devices could be accurate, fast, and cheap alternatives to standard lab tests. Researchers enrolled 149 adults with or …
Sponsor: University of Bologna • Aim: Diagnosis
Last updated Jun 27, 2026 08:03 UTC
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Could a 5-Minute nasal light zap stop surgical infections?
Prevention CompletedThis completed trial tested a device that uses light to kill germs in the nose before surgery, aiming to prevent surgical site infections. Over 400 adults having major surgeries received either the light treatment or standard care. Researchers tracked infections and side effects …
Sponsor: Ondine Biomedical Inc. • Aim: Prevention
Last updated Sep 17, 2026 00:00 UTC
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Nasal light zaps infection risk before surgery
Prevention CompletedThis study tested a new way to prevent surgical site infections by using a special light treatment inside the nose just before surgery. Over 4,700 adults having major surgeries like heart, spine, or joint replacement took part. The goal was to see if this light therapy reduces in…
Phase 3 • Sponsor: Ondine Biomedical Inc. • Aim: Prevention
Last updated Sep 17, 2026 00:00 UTC
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Alcohol lock may stop deadly infections in ICU patients
Prevention CompletedThis study tested a 60% ethanol (alcohol) lock solution to prevent serious catheter infections in 1,460 ICU patients with acute kidney failure needing dialysis. The ethanol lock is placed inside the catheter to kill germs. The goal was to see if it reduces major catheter-related …
Phase 3 • Sponsor: University Hospital, Clermont-Ferrand • Aim: Prevention
Last updated Jun 27, 2026 12:35 UTC
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Could a special light keep nursing home residents healthier?
Prevention CompletedThis study tested whether far-UVC light (222 nm) can reduce infections in elderly nursing home residents. Over 600 residents in 12 Danish facilities took part. Some facilities used the light in common areas or apartments, while others received standard care. The goal was to see i…
Sponsor: Vejle Hospital • Aim: Prevention
Last updated Jun 27, 2026 12:04 UTC
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New training helps workers with disabilities stay safe from COVID-19
Prevention CompletedThis study tested a training program called SAFE for people with intellectual or developmental disabilities who are working or looking for work. The program taught them about COVID-19, how to use protective gear, social distancing, and self-advocacy. 67 young adults took part, an…
Sponsor: Temple University • Aim: Prevention
Last updated Jun 27, 2026 09:00 UTC
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Single antibiotic dose may prevent Post-Surgery infections as well as a 5-Day course
Prevention CompletedThis study tested whether a single dose of the antibiotic fosfomycin trometamol could prevent infections after kidney stone surgery as effectively as a 5-day course of levofloxacin. 210 adults undergoing surgery were randomly assigned to one of the two treatments or a control gro…
Sponsor: Tanta University • Aim: Prevention
Last updated Jun 27, 2026 08:12 UTC
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Cow colostrum may shield kids from recurrent UTIs
Prevention CompletedThis study tested whether a supplement made from bovine colostrum (the first milk from cows) can prevent repeated urinary tract infections (UTIs) in children. Sixty children with a history of recurrent UTIs took part. The goal was to see if this natural prebiotic could reduce the…
Phase 2 • Sponsor: Ain Shams University • Aim: Prevention
Last updated Jun 27, 2026 08:08 UTC
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Simple hygiene advice may protect unborn babies from common virus
Prevention CompletedThis study tests whether teaching pregnant women about hygiene habits can reduce their risk of catching cytomegalovirus (CMV) and passing it to their baby. Researchers will enroll 200 pregnant women in Brazil and provide counseling on behaviors like handwashing. The goal is to cu…
Sponsor: University of Alabama at Birmingham • Aim: Prevention
Last updated Jun 27, 2026 08:01 UTC
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Flu shot linked to fewer deaths after fractures in seniors
Prevention CompletedThis study looked at over half a million older adults in Taiwan who were hospitalized for a bone fracture. Researchers compared those who had received a flu vaccine in the past year to those who had not. They found that vaccinated patients had fewer infections and a lower chance …
Sponsor: Taipei Medical University Hospital • Aim: Prevention
Last updated Jun 27, 2026 07:58 UTC
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New strategy aims to boost COVID-19 shots in pregnancy
Prevention CompletedThis completed trial tested a program to increase COVID-19 vaccination among pregnant women. Over 6,900 participants were involved across OB/GYN practices. The program included training for healthcare providers, reminders, and feedback on vaccination rates. The goal was to see if…
Sponsor: University of Rochester • Aim: Prevention
Last updated Jun 26, 2026 14:21 UTC
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Hernia surgery showdown: 3 stitches vs 1 stitch for mesh fixation
Symptom relief CompletedThis study compared using 3 points versus 1 point to fix a lightweight mesh during laparoscopic hernia repair (TAPP) in 351 adults with a first-time inguinal hernia. The goal was to see which method leads to less pain, fewer complications like seroma or infection, and lower recur…
Sponsor: Nanchong Central Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 12:05 UTC
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Good bacteria cream may heal skin in obesity
Symptom relief CompletedThis study tested if a cream with live good bacteria (Lactobacillus crispatus) could improve skin barrier damage in people with obesity. 98 adults aged 18-40 with a BMI of 25 or higher applied the cream or a placebo to their forearms daily for 4 weeks. The main goal was to see if…
Sponsor: Shenzhen People's Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 08:07 UTC
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New study aims to reduce infections after esophagus cancer surgery
Knowledge-focused CompletedThis study reviews medical records of 350 adults who had surgery for esophageal cancer in France between 2017 and 2024. Researchers want to understand how often infections happen after surgery, what causes them, and how they affect recovery. The goal is to find ways to prevent th…
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Sep 16, 2026 00:00 UTC
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Can software make hospital pharmacists faster and safer?
Knowledge-focused CompletedThis study tests whether a software tool called Synapse Medicine can help hospital pharmacists who work with medical teams make better and faster medication recommendations. The tool analyzes each patient's health information to flag potential drug-related risks, such as harmful …
Sponsor: Brigham and Women's Hospital • Aim: Knowledge-focused
Last updated Sep 05, 2026 00:00 UTC
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Do future doctors know the skin risks of tattoos and piercings?
Knowledge-focused CompletedThis study surveys medical students to understand their attitudes toward tattoos and piercings and measure their awareness of related skin risks, such as infections, allergic reactions, and scarring. Researchers aim to see if students have adequate knowledge and how their views d…
Sponsor: Biruni University • Aim: Knowledge-focused
Last updated Jul 30, 2026 00:00 UTC
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Researchers dive deep into mysterious lung disease
Knowledge-focused CompletedThis study looked at 275 adults with a lung condition called bronchiectasis, where airways are stretched and trap mucus, leading to infections. The goal was to learn more about the physical traits, lung scans, and germs in the lungs of people with the unexplained form of the dise…
Sponsor: National Heart, Lung, and Blood Institute (NHLBI) • Aim: Knowledge-focused
Last updated Jul 30, 2026 00:00 UTC
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Can a simple shot under the skin replace an IV for a key antibiotic in the elderly?
Knowledge-focused CompletedThis trial looks at whether giving the antibiotic ertapenem as a shot under the skin works as well as giving it through a vein in people aged 75 and older who have infections. Many older patients have poor veins or behavioral issues that make IV access difficult. The study will m…
Phase 4 • Sponsor: University Hospital, Bordeaux • Aim: Knowledge-focused
Last updated Jul 29, 2026 00:00 UTC
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Could your workout change the germs in your mouth?
Knowledge-focused CompletedThis study looks at how different amounts of endurance exercise—from none to high levels—affect the bacteria living in the mouth of young adults aged 18 to 30. Researchers will collect saliva and gum samples to compare the oral microbiome and signs of inflammation. The goal is to…
Sponsor: Centre Hospitalier Universitaire de Nice • Aim: Knowledge-focused
Last updated Jul 02, 2026 00:00 UTC
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New sensor could spot newborn infections before they turn deadly
Knowledge-focused CompletedThis study looked at 68 newborns to see if a non-invasive light sensor, which measures blood flow under the skin (called perfusion index), could help spot infections early. Newborn infections are hard to detect because signs are subtle, and delays can be dangerous. The researcher…
Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:03 UTC
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Researchers hunt for clues to predict deadly pancreas infection
Knowledge-focused CompletedThis study reviewed medical records of 148 adults admitted to the ICU with severe acute pancreatitis. The goal was to find risk factors for infected pancreatic necrosis, a serious complication that raises the risk of death. By identifying these factors, doctors hope to diagnose a…
Sponsor: Nantes University Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:03 UTC
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ECMO Patients' antibiotic levels under the microscope
Knowledge-focused CompletedThis study looked at how the body processes an antibiotic called piperacillin in intensive care patients who are on a life-support machine (ECMO) compared to those who are not. Researchers wanted to see if ECMO changes antibiotic levels, which could affect how well the drug fight…
Sponsor: Rennes University Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:07 UTC
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Low-Flow anesthesia: safe or germ haven?
Knowledge-focused CompletedThis study checked whether using very low gas flow during anesthesia (minimal flow) leads to more germs in the breathing equipment. 140 adults having elective surgery were randomly assigned to minimal or normal flow. Researchers took swabs from the equipment and patients' noses t…
Sponsor: Ankara City Hospital Bilkent • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:04 UTC
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Healthy volunteers test two drug versions for similarity
Knowledge-focused CompletedThis study tested whether two versions of a drug called DA-2902 are processed the same way in the body. Forty healthy adults took a single dose of each version under fed conditions. The goal was to compare their safety and how the body absorbs them, not to treat any disease.
Phase 1 • Sponsor: Dong-A ST Co., Ltd. • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:00 UTC
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Digital tool helps doctors pick safer antibiotics for penicillin allergy patients
Knowledge-focused CompletedThis study tested a digital decision support tool for doctors treating hospitalized patients who report a penicillin allergy. Most people who think they are allergic to penicillin are not actually allergic, but they often receive less effective antibiotics. The tool helps doctors…
Sponsor: Althaia Xarxa Assistencial Universitària de Manresa • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:00 UTC
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Scientists crack the code of antibiotic-friendly superbug
Knowledge-focused CompletedThis study looked at 56 patients in a French hospital who had infections from a rare type of Klebsiella pneumoniae bacteria that can be treated with the common antibiotic amoxicillin. Researchers used genetic sequencing to understand why these bacteria are sensitive to amoxicilli…
Sponsor: Centre Hospitalier Universitaire de Nice • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:36 UTC
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Air filter study in cameroon operating room shows promise
Knowledge-focused CompletedThis study tested a special air filtration system in an operating room at a hospital in Cameroon. The goal was to see if the system keeps the air clean and reduces germs that can cause infections after surgery. No patients were involved—only the air and equipment were tested. The…
Sponsor: Christian Doll • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:30 UTC
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App vs. phone: which triage method guides patients better?
Knowledge-focused CompletedThis study tested whether a digital symptom checker could work as well as a traditional phone call for guiding patients to the right level of care. Researchers planned to include 120 adults from a primary care center, but only 22 took part. The main goal was to see if a larger tr…
Sponsor: Region Skane • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:28 UTC
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Video team cuts unnecessary antibiotic use in rural hospitals
Knowledge-focused CompletedThis study tested a program where rural hospitals connect with an infectious disease expert through video calls to improve antibiotic use. The goal was to reduce unnecessary antibiotics and fight drug-resistant infections. Eight VA medical centers participated, and the approach h…
Sponsor: VA Office of Research and Development • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:28 UTC
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Gut bacteria may change how drugs work in your body
Knowledge-focused CompletedThis study looked at how bacteria in the gut can change the way the body processes certain drugs. 17 healthy adults took specific medicines, and researchers measured drug levels in their blood. The goal was to better understand why people respond differently to the same drug, whi…
Phase 1 • Sponsor: Rutgers, The State University of New Jersey • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:24 UTC
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Neck stretches could tune your vagus nerve, study suggests
Knowledge-focused CompletedThis completed study tested three different intensities of gentle neck movements designed to stimulate the vagus nerve in 128 healthy adults. Researchers measured changes in heart rate, balance, pain sensitivity, and digestion (via stool samples). The goal was to find the best 'd…
Sponsor: University of Vienna • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:24 UTC
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NICU antibiotic study questions routine use for tiniest babies
Knowledge-focused CompletedThis study looked at whether giving antibiotics early to extremely low birthweight babies (born before 31 weeks) might cause more harm than good. Researchers compared babies who got standard antibiotics to those who got a placebo. The goal was to see if early antibiotics increase…
Phase 4 • Sponsor: Michael Morowitz • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC
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Sweetener tagatose may tame blood sugar and feed good gut bugs
Knowledge-focused CompletedThis study tested whether tagatose, a low-calorie sweetener, can act as a prebiotic—meaning it selectively feeds beneficial gut bacteria and improves blood sugar control. Fifty-nine healthy adults with slightly high blood sugar or insulin resistance took either tagatose or a plac…
Sponsor: PepsiCo Global R&D • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC
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Gut check: could your microbiome predict heart attack outcomes?
Knowledge-focused CompletedThis study looked at the gut bacteria of 200 heart attack patients, comparing those with high blood sugar to those with normal levels. Researchers collected stool samples before treatment and again at 6 and 12 months to see if changes in gut bacteria relate to survival. The goal …
Sponsor: University of Campania Luigi Vanvitelli • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC
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Plasma power: can it keep dental implants clean?
Knowledge-focused CompletedThis study looked at whether treating the healing caps placed on dental implants with cold plasma can reduce early bacterial buildup. Twelve people each received four implants, and each implant got a different plasma treatment or none. The healing caps were removed after one week…
Sponsor: Kahramanmaras Sutcu Imam University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC
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Scientists test new ways to deliver vaccines through nose and mouth
Knowledge-focused CompletedThis early-phase study in 40 healthy adults explores how the immune system reacts to the non-toxic part of cholera toxin (CTB) when given through the nose, mouth, or under the tongue. The goal is to understand mucosal immune responses, which could help in developing future vaccin…
Phase 1 • Sponsor: Centre Hospitalier Universitaire de Nice • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:02 UTC
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Video boosts patient understanding before medical exams?
Knowledge-focused CompletedThis study looked at whether showing patients a short video, along with the usual oral and written information, helps them better understand upcoming medical exams for infectious diseases. 97 adults hospitalized in a French hospital took part. Researchers measured how well patien…
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:00 UTC
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Large study aims to uncover who is most at risk from listeria infection
Knowledge-focused CompletedThis study looked at over 2,100 people with listeriosis, a serious foodborne infection that can cause blood infections, brain infections, and pregnancy complications. Researchers collected data to find out which clinical, biological, and genetic factors make someone more likely t…
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:00 UTC
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Hospital screening study aims to predict superbug infections
Knowledge-focused CompletedThis completed study looked at whether screening hospital patients for multidrug-resistant gram-negative bacteria can predict if they will later develop an infection. Researchers reviewed records of nearly 2,900 adults admitted to an acute care hospital. The goal was to see if ea…
Sponsor: Methodist Health System • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:00 UTC
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Antibiotic drip showdown: continuous vs. intermittent for bone infections
Knowledge-focused CompletedThis study looked at two different ways of giving the antibiotic cloxacillin to treat bone and joint infections caused by Staphylococcus aureus bacteria. Twelve patients received the drug both as a steady drip (continuous infusion) and as short doses (intermittent infusion) to se…
Sponsor: Centre Hospitalier Universitaire de Nice • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:00 UTC
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Expert advice slashes unnecessary antibiotic prescriptions in family clinics
Knowledge-focused CompletedThis study tested whether adding infectious disease experts to primary care teams helps reduce unnecessary antibiotic use. Over 1,300 patients from six clinics in Spain took part. Doctors in the expert-advised group could call or meet with specialists to discuss tricky cases. The…
Sponsor: Institut d'Investigació Biomèdica de Bellvitge • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:00 UTC
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AI may predict patient decline at home before it happens
Knowledge-focused CompletedThis study tested a machine learning algorithm to predict if a patient being cared for at home would deteriorate. Researchers used data from over 500 patients to train the algorithm and compared its alerts to traditional vital sign alarms. The goal is to catch problems earlier an…
Sponsor: Brigham and Women's Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:03 UTC
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AI predicts hospital comebacks: a data dive
Knowledge-focused CompletedThis study looked at data from 372 patients to see if a computer program could predict who would need to be readmitted to the hospital within 30 days. Researchers used information like age and health history to train the computer model. The goal was to find patterns that could he…
Sponsor: Brigham and Women's Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:02 UTC
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Can a simple change in antibiotic dosing help obese patients?
Knowledge-focused CompletedThis study looked at whether giving an antibiotic (piperacillin-tazobactam) as a longer infusion helps people with obesity reach the right drug levels in their blood. It included 45 hospitalized adults with a BMI of 30 or higher. The main goal was to see if a larger study is poss…
Phase 4 • Sponsor: CR-CSSS Champlain-Charles-Le Moyne • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:02 UTC
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Breast milk from donors may help Antibiotic-Exposed Newborns' gut health
Knowledge-focused CompletedThis pilot study looked at whether giving donor human milk instead of formula to full-term babies whose mothers received antibiotics during labor could improve their gut bacteria and health. The study included 105 infants born vaginally at full term. Researchers compared the babi…
Sponsor: University of Calgary • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:07 UTC
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Extreme running may temporarily weaken immune system, study suggests
Knowledge-focused CompletedThis study looked at whether running an ultratrail (a very long race) raises the risk of getting an infection afterward. Researchers followed 471 runners and their companions, asking about symptoms like fever, sore throat, and fatigue for three weeks after the race. The goal was …
Sponsor: Centre Hospitalier Universitaire de la Réunion • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:05 UTC
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New azithromycin gel shows promise in early absorption study
Knowledge-focused CompletedThis study looked at how a new gel version of the antibiotic azithromycin is absorbed by the body compared to the standard pill. Eighteen healthy adults took the drug in different forms (oral gel, rectal gel, and standard pill) on separate days. The goal was to measure drug level…
Phase 1 • Sponsor: Brigham and Women's Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:01 UTC
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Disposable scope could cut infection risk in ERCP
Knowledge-focused CompletedThis study tested a new single-use duodenoscope (aScope) in 59 patients at high risk of infection after ERCP, a procedure to treat bile duct problems. The goal was to see if the scope works well and to gather information on costs and complications. The results could help decide i…
Sponsor: Nottingham University Hospitals NHS Trust • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:12 UTC
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Which prostate biopsy method is safer and better at finding cancer?
Knowledge-focused CompletedThis study compared two common methods for taking a prostate biopsy: one through the rectal wall and one through the skin between the scrotum and anus. 840 men who needed a biopsy for suspected prostate cancer were randomly assigned to one of the two methods. The goal was to see …
Sponsor: Albany Medical College • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:05 UTC
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Jaw surgery paste under scrutiny: does it raise infection risk?
Knowledge-focused CompletedThis study followed 196 patients who had jaw-lengthening surgery to see if using a calcium phosphate paste leads to more infections or hardware removal. The paste is meant to prevent a visible notch and improve stability. The goal was to weigh these benefits against any added ris…
Sponsor: Universitair Ziekenhuis Brussel • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:05 UTC
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Dairy fat and fermentation: surprising effects on gut bugs and heart risk?
Knowledge-focused CompletedThis study looked at how full-fat and fat-free milk and yogurt affect the gut microbiome and heart disease risk factors. 37 adults over 50 drank specially prepared dairy drinks for a period. Researchers measured changes in gut bacteria, metabolic byproducts, and blood markers to …
Sponsor: Tufts University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:03 UTC
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New malaria drug put to the test in human trial
Knowledge-focused CompletedThis study tested a new experimental drug called MMV367 in 12 healthy adults. Participants were intentionally infected with a controlled, low-level malaria infection to see how well the drug works and how safe it is. The goal was to measure how the body processes the drug and how…
Phase 1 • Sponsor: Medicines for Malaria Venture • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:03 UTC
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ICU antibiotic dosing: what really matters?
Knowledge-focused CompletedThis study looked at 156 critically ill patients to find out what factors help achieve the right levels of beta-lactam antibiotics in the blood. Researchers collected clinical data and used therapeutic drug monitoring to see which patients reached target concentrations. The goal …
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:01 UTC
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Could a simple drink before pregnancy shape your child's future health?
Knowledge-focused CompletedThis study followed 461 children whose mothers took a special nutritional drink before and during pregnancy. Researchers want to understand how parents' diet, lifestyle, and metabolism influence child growth, thinking skills, and overall well-being. The goal is to identify factor…
Sponsor: University of Southampton • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:58 UTC
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Facemasks tested for safety in endoscopy procedures
Knowledge-focused CompletedThis study looked at whether wearing a special facemask during upper endoscopy (a procedure to examine the stomach and esophagus) can reduce the spread of tiny particles into the air. The goal was to better understand infection risks, like COVID-19, for healthcare workers. Resear…
Sponsor: Anthony Lembo • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:57 UTC
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3D printed vs. traditional aligners: which hosts more mouth bacteria?
Knowledge-focused CompletedThis completed study at the University of Michigan compared how much bacteria builds up on 3D printed clear aligners versus conventional thermoformed aligners. Thirty participants wore each type of aligner for one week, and researchers swabbed both the aligners and tooth surfaces…
Sponsor: University of Michigan • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:56 UTC
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Hospital video teaches patients how to bathe to beat infections
Knowledge-focused CompletedThis study tested whether showing hospitalized patients a short video about chlorhexidine bathing could improve how well they follow the bathing instructions. Chlorhexidine bathing is known to reduce serious bloodstream infections from central lines, but many patients do not do i…
Sponsor: Duke University • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:54 UTC
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Study links vaginal germs to preterm birth risk
Knowledge-focused CompletedThis study followed 603 pregnant women in South Africa to see if infections or bacteria in the vagina are linked to how early they give birth. Researchers tested for sexually transmitted infections, yeast, and other germs at the start of pregnancy and again at 30-34 weeks. The go…
Sponsor: University of Bern • Aim: Knowledge-focused
Last updated Jun 26, 2026 18:35 UTC
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Gut bugs linked to pancreatic cancer spread in new study
Knowledge-focused CompletedThis study looked at whether the types of bacteria in the gut are linked to whether pancreatic cancer has spread to nearby lymph nodes. Researchers compared stool samples from 55 patients with and without lymph node spread. They hope to find bacterial and chemical clues that coul…
Sponsor: Peking Union Medical College Hospital • Aim: Knowledge-focused
Last updated Jun 26, 2026 14:25 UTC
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Cancer Patients' COVID-19 immune response under the microscope
Knowledge-focused CompletedThis study followed 153 people with cancer who had or were suspected of having COVID-19. Researchers collected throat swabs and saliva samples over several weeks to see how well antibody and antigen tests work in this group. The goal was to learn more about the course of COVID-19…
Sponsor: Royal Marsden NHS Foundation Trust • Aim: Knowledge-focused
Last updated Jun 26, 2026 14:13 UTC