Fingerprick test could speed up detection of blood clots and infections
NCT ID NCT04375982
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested whether a quick fingerstick blood test for D-Dimer (clot marker) and CRP (inflammation marker) gives the same results as standard lab tests using blood from a vein. Researchers enrolled 111 adults and compared results from fingerstick, venous whole blood, and plasma samples. The goal is to see if these point-of-care tests can reliably help doctors diagnose conditions like blood clots or infections faster.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this could allow doctors to quickly test for blood clots or infections using a simple fingerstick, speeding up diagnosis and treatment decisions.
- What could go wrong
- This is a small, completed study focused on comparing test methods, not on patient outcomes. The tests may not be as accurate in real-world settings or for all patient groups.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
-
111 people
The number who actually took part.
- Started
-
Apr 2020
- Finished
-
Apr 2022
- Lead sponsor
-
A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Subjects \>18 years old presenting to primary care provider with a variety of conditions as described in Inclusion/Exclusion criteria.
- Ages
-
18 years and older
- Sex
-
Anyone
- Healthy volunteers
-
Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria D-dimer: * Subjects \>18 years of age. * Willing and able to provide written informed consent and comply with study procedures. * Presenting to healthcare provider for any reason\* \*All presentations are suitable for recruitment; however, the following conditions are of particular interest: Venous thromboembolism symptoms (DVT and Pulmonary embolism), subjects seeking medical attention with symptoms of respiratory tract infection (upper or lower), Acute myocardial infarction / unstable angina, Anti-inflammatory medication (current), Any regular medication for a chronic condition (other than simple painkiller or inhaler), Atrial fibrillation, Diabetes mellitus (all types except 'pre-diabetes'), Heart failure, Hypertension (\>150/90), Infection (significant current or within 3 months), Peripheral arterial disease, Surgery (within 6 weeks), Childbirth (within 8 weeks), Significant trauma, burns (within 4 weeks), Pregnancy (confirmed or suspected), Acute upper gastrointestinal haemorrhage other significant recent haemorrhage. D-dimer Exclusion Criteria: * The subject is currently receiving or has received within the past thirty (30) days of the study visit an experimental biologic or drug including either treatment or therapy. * Skin lesions or conditions that would preclude a fingerstick and or a venous blood draw. * End-stage renal failure on haemodialysis. * Life expectancy documented as less than 30 days. * Haemodynamically unstable (e.g. cardiogenic shock). * Current anticoagulation therapy (Fragmin, LMWH) within the last 30 days. * Patients taking anticoagulant therapy (DOACS, Warfarin, Heparins etc.) within the last 30 days. * The subject has previously participated in this research study CRP Inclusion criteria: * Subjects \>18 years of age. * Willing and able to provide written informed consent and comply with study procedures. * Subjects seeking medical attention with symptoms of infection, tissue injury, inflammatory disorders or associated disease. This includes but not limited to: respiratory tract infection (upper or lower), rheumatoid arthritis, Lupus, burns, trauma, inflammatory bowel disease. CRP Exclusion Criteria: * The subject is currently receiving or has received within the past thirty (30) days of the study visit an experimental biologic or drug including either treatment or therapy. * Skin lesions or conditions that would preclude a fingerstick and or a venous blood draw. * A subject with a critical illness, requiring critical intervention, or end of life or palliative care. * Subjects suffering with Myeloma, Monoclonal Gammopathy or extreme Lipaemia. * The subject has previously participated in this research study
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Embolism and thrombosis are added.
Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Centura Health Physician Group
Northglenn, Colorado, 80234, United States
-
Diagnostic Clinic of Longview
Longview, Texas, 75605, United States
-
New Medical Healthcare
Wichita, Kansas, 67212, United States
-
Rancho Paseo Medical Group
Banning, California, 92220, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Clotting clues: simple blood test eyed to catch sepsis before it turns deadly
- Can a berry extract help athletes bounce back after brutal workouts?
- Can PET scans reveal hidden heart inflammation after a stroke?
- After a stroke, does the heart inflame? MRI study probes the link
- 150,000 children to be tracked from birth to old age in massive health study
- Blood clues in depression: immune signals may flag who benefits from SSRIs