Crimean-Congo hemorrhagic fever
MONDO:0020501Crimean-Congo hemorrhagic fever (CCHF) is a tick-borne zoonotic disease caused by CCHF virus and characterized by initial fever, headache, and malaise followed by gastrointestinal symptoms and, in severe cases, bleeding, shock, and multi-organ system failure.
Also known as: CCHF, Congo fever, Congo hemorrhagic fever, Congo-Crimean hemorrhagic fever, Crimean hemorrhagic fever, Crimean hemorrhagic fever [CHF Congo virus], Crimean-Congo haemorrhagic fever
8 clinical trials for this condition and its sub-types, 5 tagged with Crimean-Congo hemorrhagic fever itself.
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Supercharged donor cells take on viruses after transplant
Disease control Recruiting nowThis study tests whether specially grown donor immune cells (viral-specific T-cells) can safely treat viral infections that often occur after a stem cell transplant. These infections can be serious and sometimes don't respond to standard antiviral drugs. The approach aims to boos…
Phase 1/2 • Sponsor: Children's Hospital Medical Center, Cincinnati • Aim: Disease control
Last updated Sep 06, 2026 00:00 UTC
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Can donor cells stop viruses after transplant?
Disease control Recruiting nowThis study tests whether giving patients donor-derived immune cells (VSTs) on a regular schedule can prevent dangerous viral infections after a stem cell transplant. 180 participants will be randomly assigned to receive VSTs either on a fixed schedule or only when a virus is dete…
Phase 2 • Sponsor: Children's Hospital Medical Center, Cincinnati • Aim: Disease control
Last updated Sep 06, 2026 00:00 UTC
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Can antivirals tame a deadly Tick-Borne virus?
Disease control Recruiting nowThis trial tests whether two antiviral drugs, favipiravir and ribavirin, can help clear the virus faster in adults hospitalized with Crimean-Congo hemorrhagic fever (CCHF), a severe tick-borne infection. Participants will receive one of the drugs or optimized standard care, and r…
Phase 2 • Sponsor: Liverpool School of Tropical Medicine • Aim: Disease control
Last updated Aug 09, 2026 00:00 UTC
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New 20-Minute test could spot deadly virus at bedside
Diagnosis Recruiting nowThis study is testing a new rapid diagnostic test for Crimean-Congo hemorrhagic fever (CCHF) that gives results in 20 minutes. Researchers will enroll 492 adults in Turkey with suspected CCHF to see if the test is accurate compared to standard lab methods. The goal is to provide …
Sponsor: Liverpool School of Tropical Medicine • Aim: Diagnosis
Last updated Jun 27, 2026 13:05 UTC