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Could your workout change the germs in your mouth?

NCT ID NCT05765422

Knowledge-focused Sponsor: Centre Hospitalier Universitaire de Nice Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 30, 2026 · Last updated Jul 01, 2026 · Updated 1 time

Summary

This study looks at how different amounts of endurance exercise—from none to high levels—affect the bacteria living in the mouth of young adults aged 18 to 30. Researchers will collect saliva and gum samples to compare the oral microbiome and signs of inflammation. The goal is to understand whether exercise level is linked to oral health and to find mouth-based markers of physical activity.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could reveal how different levels of exercise shape the mouth's microbial balance, pointing toward simple oral-health checks for athletes.
What could go wrong
This is a small pilot study, so findings may not apply broadly. It only looks at young endurance athletes, and results are observational—no treatment is tested.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

103 people

The number who actually took part.

Started

Oct 2022

Finished

Jan 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 30 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Be between 18 and 30 years old * If practicing sports, it must be an endurance sport as main activity (cycling or running) Exclusion Criteria: * Practice more than 3 hours of swimming per week * Have taken anti-inflammatory drugs, less than 48 hours before the study * Have taken antibiotics and/or probiotics, less than 3 weeks before the study

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Conditions

The condition(s) this trial relates to.

infectious disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Microbial colonization

Contacts and locations

Locations

  • Nice University Hospital

    Nice, 06000, France

More trials for these conditions

Other studies related to the condition(s) this trial covers.