Expert advice slashes unnecessary antibiotic prescriptions in family clinics
NCT ID NCT04848883
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether adding infectious disease experts to primary care teams helps reduce unnecessary antibiotic use. Over 1,300 patients from six clinics in Spain took part. Doctors in the expert-advised group could call or meet with specialists to discuss tricky cases. The goal was to see if this support leads to fewer and better antibiotic prescriptions for common infections like colds and urinary tract infections.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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1,389 people
The number who actually took part.
- Started
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Jun 2021
- Finished
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Jun 2024
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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15 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion criteria at centre-level (clusters) * Primary care centres belonging to the Delta del Llobregat healthcare area. * Prior experience in clinical research and formal agreement to participate in the study. * Comparability of their reference populations. All general practitioners of the 6 primary care centers will be included in our clinical trial, excepting paediatricians. Data collection will be performed on patients attended in these centres. Inclusion and exclusion criteria will be applied on the patients attended by general practitioners: Inclusion criteria at patient-level criteria (unit for secondary objectives) * Adult patients (aged \>14 years). * Diagnosed with an acute URTI (including pharyngoamygdalitis, sinusitis, otitis) or UTI (including cystitis, prostatitis, pyelonephritis) during the study period. * Patients attended by a GP at the selected centres. Eligible patients will be identified following the International Classification of Diseases (ICD-10) CM codes as follows: * URTI: J00, J01, J02, J03, J04, J05, J06, J31, J39, H60, H62, H65, H66, H67, H83 and H92. * UTI: N10, N30, N39, N41, R82 and O23. Exclusion criteria: * Patients less than 14 years old. * Patients with indwelling urinary catheter. * Patients with congenital urinary tract abnormalities. * Pregnant women. * Patients undergoing urological surgery.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Hospital Univeristari de Bellvitge
Barcelona, Catalonia, s/n, Spain
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Home hospital care for infections: when does it fail?