Bird flu booster shows promise in early trial
NCT ID NCT05422326
First seen May 13, 2026 · Last updated Jun 22, 2026 · Updated 5 times
Summary
This study tested whether a booster shot for H5N6 bird flu could boost immunity in adults who had either received an H5N1 vaccine or a placebo in a previous study. About 260 adults took part, receiving one or two doses of the H5N6 vaccine. Researchers measured antibody levels to see how well the booster worked.
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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AccellaCare
Winston-Salem, North Carolina, 27103, United States
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Aventiv Research
Columbus, Ohio, 43213, United States
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Biogenics Research Institute
San Antonio, Texas, 78229, United States
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California Research Foundation
San Diego, California, 92103, United States
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Clinical Research Consortium Arizona
Tempe, Arizona, 85283, United States
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Clinical Research Consulting, LLC
Milford, Connecticut, 06460, United States
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Great Lakes Clinical Trials LLC
Chicago, Illinois, 60640, United States
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Heartland Research Associates, LLC
Wichita, Kansas, 67207, United States
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Innovative Research of West Florida, Inc.
Clearwater, Florida, 33756, United States
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J. Lewis Research, Inc/Foothill Family Clinic North
Salt Lake City, Utah, 84109, United States
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J. Lewis Research, Inc/Foothill Family Clinic South
Salt Lake City, Utah, 84121, United States
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J. Lewis Research, Inc/Jordan River Family Medicine
South Jordan, Utah, 84095, United States
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Optimal Research, LLC
Huntsville, Alabama, 35802, United States
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Optimal Research, LLC
Melbourne, Florida, 32934, United States
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PMG Research of Raleigh
Raleigh, North Carolina, 27609, United States
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Rochester Clinical Research, Inc
Rochester, New York, 14609, United States
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Sundance Clinical Research, LLC
St Louis, Missouri, 63141, United States
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The Center for Pharmaceutical Research
Kansas City, Missouri, 64114, United States
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
MF59-adjuvanted H5N6 influenza vaccine
What this could lead to
If successful, this could help develop a strategy to protect people against different bird flu strains using a booster shot.
What could go wrong
This is a Phase 2 study with only 260 participants, so results may not apply to everyone. The vaccine targets a specific bird flu strain that may not match future outbreaks.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.