Influenza, human

This large phase 3 trial compares an investigational mRNA flu vaccine with a licensed flu vaccine in adults aged 65 and older. Each participant receives a single injection and is followed through the flu season. Researchers measure how well the mRNA vaccine prevents laboratory-co…

This study tests a new seasonal flu vaccine that includes an adjuvant (ZFA02) to potentially boost the immune response. The trial involves 620 adults aged 18 and older, split into low-dose and high-dose groups, with some receiving a placebo. Researchers will monitor side effects …

This early-stage trial is testing whether a COVID-19 vaccine and a flu vaccine can be given together as a liquid under the tongue instead of a shot. About 100 adults will receive both vaccines over four months. The goal is to see if this approach is safe and triggers a strong imm…

This early-stage trial tests a new drug called PRS CK STORM, made from a mix of immune and fat cells, to see if it can safely calm the 'cytokine storm'—a dangerous overreaction of the immune system—in people with severe lung infections from COVID-19, flu, or RSV. The study will e…

This study compares different antiviral drugs to see which one clears the flu virus fastest. It involves 3,000 adults aged 18-60 with early flu symptoms. Participants are randomly assigned to receive a drug or no treatment, and their viral levels are tracked daily for a week.

This study looks at how your immune system reacts when you get the flu. Researchers want to see if your body mostly uses memories from past flu infections or builds a brand new defense. About 50 adults with a confirmed flu will provide blood and nasal samples to help answer this …

This study looks at how a person's birth year and past flu exposure affect their immune response to the seasonal flu vaccine. Researchers will enroll up to 700 healthy adults of different ages to measure antibodies and immune cells before and after vaccination. The goal is to und…