New DNA test could speed up bone infection diagnosis
NCT ID NCT07256405
First seen Jun 27, 2026 · Last updated Jul 08, 2026 · Updated 2 times
Summary
This study looks at whether a new DNA sequencing technology (Nanopore) can better identify infections in broken bones compared to standard lab cultures. Researchers will collect bone samples from 100 adults with fracture-related infections and compare the results from both methods. The goal is to see if this faster approach can help doctors choose the right antibiotics sooner.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
-
100 people
The number who actually took part.
- Started
-
Mar 2024
- Finished
-
Dec 2025
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Patients admitted to hospital following trauma for whom a fracture-related infection was diagnosed.
- Ages
-
18 years and older
- Sex
-
Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age ≥ 18 years * Diagnosis of fracture-related infection (FRI consensus group) * Patient scheduled to undergo a bone and/or soft-tissue biopsy as part of routine care Exclusion Criteria: * Patient opposition * Patient under a legal protection measure.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for BONE are added.
Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
IHU, service des maladies infectieuses chroniques
Marseille, Bouches-du-Rhône, 13005, France
-
Military Teaching Hospital Sainte Anne
Toulon, VAR, 83000, France
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can a new knee implant design offer better Long-Term relief?
- Can a simple blood test predict sepsis two days early?
- Switching stomach drugs after transplant may tame a deadly immune attack
- Can telemedicine bring IV antibiotics home?
- Blood test may forecast recovery in elderly infection patients
- Aging in place: could mobile teams keep nursing home residents out of the hospital?