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Can a simple change in antibiotic dosing help obese patients?

NCT ID NCT06690905

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at whether giving an antibiotic (piperacillin-tazobactam) as a longer infusion helps people with obesity reach the right drug levels in their blood. It included 45 hospitalized adults with a BMI of 30 or higher. The main goal was to see if a larger study is possible, not to prove the treatment works better.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 4

Runs after approval, following long-term safety and how well the treatment works in everyday use.

Participants

45 people

The number who actually took part.

Started

Feb 2025

Finished

Nov 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adults (18 years and older) * Patients hospitalized at Hôpital Charles-Le Moyne * Obesity (as defined by a body mass index of ≥ 30 kg/m\^2) * Piperacillin-tazobactam prescription initiated within last 24 hours * Planned duration of piperacillin-tazobactam of 24 hours or more Exclusion Criteria: * Documented allergy to beta-lactams of the penicillin class * Patients with renal replacement therapy (hemodialysis, peritoneal dialysis, continuous venovenous hemodiafiltration) * Pregnancy * History of seizures or epilepsy, active seizures or epilepsy treated with antiepileptic drug therapy * Patients on prolonged intermittent infusion or continuous infusion of piperacillin-tazobactam before randomization

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Hôpital Charles- Le Moyne

    Greenfield Park, Quebec, J4V 2H1, Canada

More trials for these conditions

Other studies related to the condition(s) this trial covers.