Flu shot linked to fewer deaths after fractures in seniors
NCT ID NCT07231016
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at over half a million older adults in Taiwan who were hospitalized for a bone fracture. Researchers compared those who had received a flu vaccine in the past year to those who had not. They found that vaccinated patients had fewer infections and a lower chance of dying within 30 days after their fracture.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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561,566 people
The number who actually took part.
- Started
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Nov 2019
- Finished
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Jan 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
This study utilized a nationwide, population-based cohort encompassing over twenty million insured individuals. From this cohort, we identified older adults admitted for fracture treatment between 2009 and 2020. Among them, approximately two in five had received an influenza vaccination within the year before hospitalization. To minimize confounding, we performed one-to-one propensity score matching, pairing each vaccinated patient with an unvaccinated counterpart based on demographic, socioeconomic, and clinical characteristics, including age, sex, income status, fracture type, comorbidities, and prior healthcare utilization.
- Ages
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20 days and older
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: Patients with fracture hospitalization who aged more than 65 years Exclusion Criteria: People had no fracture hospitalization and people aged lower than 65 years
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Taipei Medical University Hospital
Taipei, 110, Taiwan
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Other studies related to the condition(s) this trial covers.
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