Researchers hunt for clues to predict deadly pancreas infection
NCT ID NCT03253861
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study reviewed medical records of 148 adults admitted to the ICU with severe acute pancreatitis. The goal was to find risk factors for infected pancreatic necrosis, a serious complication that raises the risk of death. By identifying these factors, doctors hope to diagnose and treat the infection earlier.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this study could help doctors identify which patients are at higher risk for infected pancreatic necrosis, leading to earlier treatment and better outcomes.
- What could go wrong
- This is a retrospective study, meaning it looks back at past data. It cannot prove cause and effect, and the findings may not apply to all patients.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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148 people
The number who actually took part.
- Started
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Jun 2016
- Finished
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Jun 2017
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Adult patients with acute necrotizing pancreatitis admitted in an ICU between January 2012 and December 2015 for moderately severe or severe acute pancreatitis
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Adult patients (age \>18 years) with acute necrotizing pancreatitis admitted in an ICU between January 2012 and December 2015 for moderately severe or severe acute pancreatitis were included. * Organ failure that resolves within 48 h (transient organ failure) and/or local or systemic complications without persistent organ failure or persistent organ failure (\>48 h) Exclusion Criteria: * mild acute pancreatitis, defined as no organ failure or local complication (No necrosis or peri-pancreatic collection)
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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CHU de Nantes
Nantes, 44093, France
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Other studies related to the condition(s) this trial covers.
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