PANCREATITIS

This study tests a device called RELiZORB that adds digestive enzymes directly to liquid food given through a feeding tube. It is for people who have trouble digesting food after pancreatitis. The goal is to see if it improves symptoms and quality of life. About 60 adults will ta…

This study tests whether giving a short course of two medicines (hydrocortisone and octreotide) plus using a patch made from the patient's own tissue during surgery can lower the risk of serious complications after Whipple surgery. The trial includes 400 adults with a small pancr…

This study tests whether giving a short course of intravenous hydrocortisone, an anti-inflammatory drug, to adults with severe acute pancreatitis can reduce inflammation and improve recovery. About 86 participants in intensive care will receive either the drug or a placebo. The g…

This study looks at whether a urine dipstick test can quickly detect pancreatitis after pancreas removal surgery. About 50 adults having elective pancreatectomy will provide urine samples before, during, and after surgery. The goal is to see if this simple test works as well as s…

This study tests whether spraying nitroglycerin directly into the bile duct during an ERCP procedure can prevent pancreatitis, a common and serious complication. About 440 adults who need a stone removed from their bile duct will take part. Half will get the nitroglycerin spray d…

This study compares two common anti-inflammatory drugs given as suppositories to prevent pancreatitis after a routine ERCP procedure. About 4,050 adults aged 18-90 who need ERCP will be randomly assigned to receive either indomethacin or diclofenac before the procedure. The goal …

This study tests whether rinsing the bile duct opening with cold water at the end of an ERCP procedure, in addition to standard medication, can lower the chance of developing pancreatitis—the most common serious complication after ERCP. About 950 adults with a natural bile duct o…

This study tests Scrambler Therapy, a non-invasive device that sends electrical signals through the skin to retrain how the brain perceives pain. Adults with chronic pancreatitis and persistent abdominal pain not helped by standard treatments will receive 5-10 sessions and be fol…

This study tests an internet-delivered pain self-management program for adults with chronic pancreatitis. The goal is to reduce pain severity and its impact on daily activities, improving quality of life. Participants use a personal device or borrow one to access the program.

This study tests a mobile app that gives personalized tips and insights based on your blood sugar, exercise, mood, and sleep patterns. The goal is to help 60 adults aged 30-65 with type 1 diabetes or similar conditions exercise more often and with greater confidence. All particip…

This study is working on a new, less invasive test to find pancreatic cancer at an early stage and to see how well treatment is working. Researchers will study 700 people with pancreatic cancer or related conditions to find biological markers in the blood or tissue. The goal is t…

This study follows 250 adults undergoing pancreatic surgery to understand how the procedure impacts their quality of life over two years. Researchers will use surveys to track changes in physical, emotional, and social well-being. The goal is to help doctors and patients make bet…

This study creates a registry for people with pancreatic diseases or a high risk of pancreatic cancer, including those with family history or certain genetic mutations. Researchers collect health data and blood samples to study causes and find early detection markers. The goal is…

This study follows over 2,300 people with and without chronic pancreatitis to learn what causes the disease and how it progresses. Researchers collect health information and symptoms over time to find better ways to treat or prevent it. Participants do not receive any experimenta…

This study is a large registry that collects data on how a blood-filtering device called CytoSorb is used in real-world intensive care settings. It will include up to 3,000 critically ill patients with conditions like septic shock, severe lung injury, or liver failure. The goal i…