University Of California, Los Angeles

This study aims to find the best ways to help people from diverse backgrounds manage their high blood pressure in Los Angeles County clinics. Researchers are testing different outreach approaches focused on either healthcare providers or patients to see which works better. The go…

This study is testing a personalized, two-step approach to help preschoolers with autism who speak very few words develop better language skills. It compares different teaching methods and adjusts the plan based on how each child responds early in treatment. The goal is to find t…

This study tests whether intensive family therapy can help young people at high risk for developing psychosis. 220 youth ages 13-25 will receive either 18 family therapy sessions or 3 family sessions plus individual support over 6 months, with follow-up for 18 months. The goal is…

This study tested whether adding a purified form of CBD (cannabidiol) oil to existing medications could help reduce seizures in children with severe, drug-resistant epilepsy. It involved 25 children aged 1-17 who had not responded to other treatments. Researchers tracked seizure …

This study is checking on children who were previously treated with an experimental gene therapy for a rare, severe immune system disorder called ADA-SCID. The goal is to see how safe and effective the treatment remains over 15 years by tracking their health, survival, and whethe…

This study is evaluating a new UCLA program called the Next Day Clinic. The goal is to see if sending certain emergency room patients with conditions like pneumonia or heart failure to a special high-acuity clinic the next day, instead of admitting them to the hospital, leads to …

This early-stage study is testing if adding the drug belumosudil to a special kidney and stem cell transplant procedure can help patients safely stop taking lifelong anti-rejection medications. The goal is to see if the body can learn to accept the new kidney without needing cons…

This study is testing if a drug called angiotensin 2, given during liver transplant surgery, can prevent kidney injury afterward. It will involve about 30 adults with severe liver disease who are receiving a transplant. Half will get the study drug along with standard medications…

This study is testing whether a personalized digital coaching program, delivered through a mobile app and a smart toothbrush, can help adults brush their teeth more consistently and effectively than traditional instructions alone. 230 adults from California community dental clini…

This study is testing a new video-chat platform called 'Tele-FootX' that guides patients through foot and ankle exercises. The goal is to see if these supervised, game-like exercises can improve blood flow to the feet and help heal diabetic foot ulcers faster. It's a small, early…

This UCLA study is testing whether adding a specialized speech therapy (PROMPT) to a proven play-based social skills program (JASPER) helps non-verbal or minimally verbal children with autism learn more words and start combining words by kindergarten age. Researchers are comparin…

This study tested whether a non-invasive brain stimulation technique called intermittent Theta Burst Stimulation (iTBS) could help people with major depression who still have symptoms despite taking medication. Participants received either real or fake stimulation sessions over t…

This early-stage study is testing whether a device implanted near the spinal cord, combined with a specific drug, can help people with severe neck-level spinal cord injuries regain some hand and arm movement. It involves up to 12 participants who are at least one year post-injury…

This study is testing if giving testosterone therapy to men with low testosterone levels helps them recover better after a kidney transplant. It will involve about 50 men who are scheduled for a transplant and have low testosterone. Researchers will compare their recovery, safety…

This early-stage study is testing a personalized treatment for people with severe damage to the clear front part of their eye (cornea). Doctors take a tiny sample of a patient's own healthy eye cells, grow them in a lab, and then transplant them back to try to repair the damaged …

This study is testing whether adding a low dose of Adderall XR makes brain stimulation therapy work better for people with depression that hasn't improved with standard medications. It will involve 30 adults who will be randomly assigned to take either Adderall or a placebo pill …

This study is testing a community-based program to improve addiction care in Vietnam. The program trains local health workers and family members to work together to support people struggling with opioid addiction. Researchers will measure whether this team approach helps people s…

This UCLA pilot study is testing whether gentle, non-invasive magnetic brain stimulation can help people with borderline personality disorder (BPD) better control their emotions and impulses. Researchers will use brain scans to find the best target for stimulation in 20 participa…

This study aimed to test a new therapy program delivered by video call for teenagers with PTSD. It planned to see if the program was practical to run, acceptable to teens and families, and if it helped improve PTSD knowledge, coping skills, and symptoms. The study was designed to…

This study is testing a new, personalized method for magnetic brain stimulation to treat severe depression. It aims to see if finding a person's unique 'brain rhythm' for treatment is safe and practical, rather than using a standard one-size-fits-all frequency. The study will inv…

This study is testing a new, personalized approach to brain stimulation therapy for major depression. Researchers are trying to find the exact stimulation frequency that works best for each person's unique brain circuit, rather than using the same frequency for everyone. The stud…

This small pilot study is checking if a special high-fat, low-carbohydrate diet (called a ketogenic diet) is safe and practical to use for children in intensive care with serious, sudden brain injuries like stroke or severe head trauma. The idea is that after an injury, the brain…

This study is testing whether adding a mobile phone self-monitoring tool to an existing brief counseling program helps people reduce their risky drug use for a full year. It involves 600 adults from community health centers in Southern California who report moderate drug use. Par…

This study is testing a new toolkit designed to help doctors' offices improve how they schedule and conduct annual wellness visits for Medicare patients. It involves over 13,000 patients across 16 primary care practices in the U.S. The goal is to see if using this toolkit leads t…

This study is testing a handheld scanner to help nursing home staff find early signs of pressure injuries (bedsores) much sooner than the eye can see. Over 4,700 residents are involved to see if using this scanner during routine checks prompts staff to start preventive care faste…

This study is testing a new support program to help pregnant and breastfeeding women in South Africa consistently take a daily pill that prevents HIV. The program offers easier access to the medication and extra counseling, especially for women who struggle to take it regularly. …

This study is testing whether a community program where older adults mentor elementary school children can help strengthen their natural defenses against respiratory viruses like colds, flu, and COVID-19. Researchers will enroll 160 older African-American adults from South Los An…

This early-stage study is testing whether a cannabis compound called cannabigerol (CBG) can help with pain relief and increasing appetite, both alone and when combined with THC. Researchers are studying 20 healthy adults who occasionally use cannabis to measure how these compound…

This study is testing whether a six-session biofeedback training program can help people with persistent shortness of breath that hasn't improved with standard medical care. The program teaches participants techniques to control their breathing, heart rate, and body temperature t…

This study aimed to compare two FDA-approved devices that help seal the artery after heart catheterization through the groin. Researchers wanted to see if using both devices together would help patients walk sooner after their procedure compared to using just one device. The tria…

This study is testing a new home exercise program for older adults with mild memory loss or dementia. Participants use a special video game system at home to do balance and thinking exercises, which are supervised remotely by a therapist through video calls. The goal is to see if…

This study aimed to explore whether using a virtual reality headset for guided mindfulness meditation could help reduce symptoms of pain, stress, anxiety, and depression. It planned to enroll 60 adults from UCLA and VA hospitals to try 15-minute VR sessions and track their sympto…

This study is testing whether a special form of magnesium, called magnesium L-threonate, can help improve sleep quality, recovery, and physical performance in college athletes. About 100 UCLA varsity athletes will take either the supplement or a placebo pill each night for four w…

This study is testing if adding a steroid to a standard pain-blocking injection helps reduce pain for longer after a uterine fibroid treatment procedure. It involves 28 women who are having a procedure called uterine artery embolization (UAE). Researchers will compare pain levels…

This small pilot study is testing whether a non-invasive brain stimulation technique called rTMS is safe and tolerable for people with Long COVID. Twenty participants with Long COVID, primarily suffering from fatigue and brain fog, will receive either real or sham (fake) stimulat…

This small study is testing whether a combination of morning light therapy and online behavioral therapy is a practical and acceptable way to help teenagers with ADHD who have very late sleep schedules. The goal is to see if this approach can shift their internal body clock to an…

This study is testing whether adding computer-based memory practice exercises to standard therapy helps veterans remember to do things later, like taking medication or keeping appointments. Researchers are comparing 75 veterans receiving either standard memory training alone or s…

This study is testing if a new type of online talk therapy, called Emotional Resolution (EmRes), can help reduce anxiety in healthcare workers. Researchers are comparing it to another online program focused on mindfulness and gratitude. About 150 healthcare workers with anxiety w…

This study aims to understand how different cues—like visual targets, rhythmic sounds, or rewards—help Parkinson's patients move more easily. Researchers will use brain scans (MRI) and brain wave recordings (EEG) on 90 participants (60 with Parkinson's, 30 healthy) while they per…

This study aimed to test if a simple, non-invasive finger cuff device could accurately measure how well the heart is pumping in patients with severe lung blood pressure conditions (PAH or CTEPH). Researchers planned to compare the finger cuff readings against standard, more invas…

This study aims to understand how the brain learns fear. Researchers will use virtual reality and safe, mild brain stimulation in 70 people who already have a brain implant for epilepsy. The goal is to map brain and body responses to fear, which could help improve future treatmen…

This early study is testing whether stimulating the brain's vision center with an implanted device can create artificial visual sensations in people who are blind. Researchers are working with 5 blind volunteers to find the right brain location and stimulation level needed to pro…

This study aimed to understand if a gas called inhaled nitric oxide (iNO) could help improve heart and lung function in patients with serious, life-threatening blood clots in the lungs (pulmonary embolism). It planned to enroll about 20 patients at UCLA Medical Center and measure…

This UCLA study aims to understand how thinking of a supportive person helps us overcome fear. Researchers will give 60 healthy adults either a drug (naltrexone) or a placebo pill, then see if it changes how well a picture of a loved one helps them learn that a previously scary c…

This study is testing whether a new AI tool can make doctors' jobs easier. The tool automatically summarizes a patient's medical chart before their visit. Researchers are measuring if this reduces the doctors' mental workload and saves them time, which could help prevent burnout …

This study aimed to test if a non-invasive finger-cuff device could safely and effectively monitor heart function in real-time for patients hospitalized with serious pulmonary embolism (a dangerous lung blood clot). The goal was to see if the device's readings could help doctors …

This UCLA study is testing whether specific cannabis compounds called terpenes affect pain relief and intoxication when used alone or with THC. Researchers are enrolling 45 regular cannabis users to measure pain responses and subjective feelings after inhaling vaporized compounds…

This study aims to understand why certain cues, like sounds or visual prompts, can help people with Parkinson's disease move more easily. Researchers will record brain activity from 40 patients during their scheduled deep brain stimulation (DBS) surgery while they perform simple …

This study aims to understand why people with Parkinson's disease experience 'freezing of gait'—a sudden inability to start or continue walking. Researchers will record brain activity from special deep brain stimulation devices while participants walk in a virtual reality environ…

This study aims to understand how a brain stimulation treatment works for major depression. Researchers will give 30 participants either a single dose of an antidepressant or a placebo, along with brain stimulation sessions, while measuring brain activity with scans and recording…

This study created a registry of over 5,000 people who have recovered from COVID-19. The purpose is to build a pool of volunteers for future research. Researchers will use this group to study immunity, test for antibodies, and identify potential donors for treatments like convale…

This international registry study aims to collect data from 10,000 patients undergoing catheter ablation procedures for dangerous heart rhythms called ventricular tachycardia. By tracking outcomes across approximately 30 medical centers worldwide, researchers hope to better under…