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Breathing without drugs: biofeedback trial aims to ease persistent shortness of breath

NCT ID NCT05973513

Symptom relief Sponsor: University of California, Los Angeles Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This UCLA study tests whether biofeedback—a technique that teaches control over heart rate, breathing, and body temperature—can relieve shortness of breath in people who haven't gotten better with inhalers or pulmonary rehab. Twenty-five adults aged 18–60 with ongoing respiratory symptoms will attend six sessions. The goal is to see if symptoms, mood, sleep, and quality of life improve.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
biofeedback (heart-rate variability training, relaxation, temperature control)
What this could lead to
If it works, this could offer a non-drug way to manage persistent breathing problems and improve quality of life.
What could go wrong
This is a small, early-stage trial with only 25 people and no comparison group, so results may not apply widely. It also relies on self-reported improvements.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 25 people

The number the study aims to enrol. It can still change while the study runs.

Started

Aug 2021

Expected to finish

Jul 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

(1) participants must be between 18-60; (2) English speaking; (3) must have least one respiratory sx and have received care from a pulmonologist for this sx

Ages

18 to 60 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. participants must be between 18-60 2. English speaking 3. must have least one respiratory sx and have received care from a pulmonologist for this sx Exclusion Criteria: severe psychopathology (e.g., psychosis, active suicidality, moderate to severe intellectual impairment).

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Conditions

The condition(s) this trial relates to.

Dyspnea

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Shortness of breath/dyspnea

Contacts and locations

Locations

  • Natacha Emerson

    Los Angeles, California, 90095, United States