Could zapping the brain rapidly reduce suicidal urges?

NCT ID NCT04197765

Ongoing Symptom relief Sponsor: University of California, Los Angeles Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This pilot study tests whether a type of brain stimulation called accelerated continuous theta-burst stimulation (acTBS) can reduce suicidal thoughts in people hospitalized for depression. Forty inpatients will receive either real or sham (fake) stimulation up to 5 times a day for about a week. Researchers will track changes in suicidal thinking and mood using questionnaires.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: accelerated continuous theta-burst stimulation (acTBS) using a transcranial magnetic stimulation device
What this could lead to: If it works, this could point toward a rapid, non-drug treatment to ease suicidal thoughts in people hospitalized with depression.
What could go wrong: This is a very small pilot study with only 40 people. It is too early to know if the treatment is effective or safe for wider use.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

major depressive disorder Suicidal Ideation

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

SUICIDALITY

Contacts and locations

Locations

Resnick Neuropsychiatric Hospital

Los Angeles, California, 90025, United States

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