Can an Anti-Inflammatory diet protect the kidneys? a trial puts the autoimmune protocol to the test

NCT ID NCT07022574

Terminated Disease control Sponsor: University of California, Los Angeles Source: ClinicalTrials.gov ↗

First seen Jul 27, 2026 · Last updated Jul 28, 2026 · Updated 1 time

Summary

This UCLA study is testing whether the Autoimmune Protocol (AIP) diet — which avoids dairy, grains, and sugar — can reduce protein levels in the urine of people with IgA nephropathy, a kidney disease that can lead to kidney failure. Thirty adults aged 18 to 65 with active disease will follow the diet for 6 months, tracking their urine protein daily and having monthly lab checks. The goal is to see if the diet can lower urine protein by 20% or more, which could help slow disease progression.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Autoimmune Protocol (AIP) diet — an anti-inflammatory eating plan that avoids dairy, grains, and sugar
What this could lead to: If the diet reduces urine protein by 20% or more, it could offer a simple way to slow kidney disease and delay the need for dialysis or other treatments.
What could go wrong: This is a small exploratory study with only 30 participants and no control group. Dietary changes can be hard to stick with, and results may not apply to everyone with IgA nephropathy.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for IGA NEPHROPATHY (IGAN) are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

IgA glomerulonephritis kidney disorder proteinuria

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

IGA NEPHROPATHY (IGAN)

Contacts and locations

Locations

UCLA

Manhattan Beach, California, 90266, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.