Needle vs. scalpel: which dialysis access works best?

NCT ID NCT05654103

First seen Jun 27, 2026 · Last updated Aug 11, 2026 · Updated 4 times

Summary

This study compares two methods for creating an arteriovenous fistula (AVF) in people with end-stage kidney disease who need dialysis. The newer endovascular method uses a needle through the skin, while the traditional surgical method requires an incision. Researchers will enroll 90 patients who qualify for both procedures and randomly assign them to one method, tracking how well the fistula matures and how long it lasts. The goal is to gather data for a larger study to determine which approach is better.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
endoAVF device and surgical AVF procedure
What this could lead to
If this trial succeeds, it could show that the newer needle-based method for creating dialysis access is as good as or better than surgery, potentially offering a less invasive option for kidney patients.
What could go wrong
This is a small pilot study with only 90 participants, so results may not apply to everyone. The newer method may require more follow-up procedures, and it's too early to know which approach is truly better.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • UCLA Division of Vascular and Endovascular Surgery Clinic

    Los Angeles, California, 90095, United States

  • University of Pittsburgh Medical Center

    Pittsburgh, Pennsylvania, 15231, United States

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