Tiny study tests diuretics for dialysis patients – terminated early

NCT ID NCT05915286

Terminated Disease control Sponsor: University of Alberta Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This pilot study tested two diuretics (furosemide and chlorthalidone) in people on dialysis who still had some kidney function. The goal was to see if these water pills could help preserve remaining kidney function, increase urine output, and reduce weight gain between dialysis sessions. Only 2 participants were enrolled, and the study was terminated early, so no firm conclusions can be drawn.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Furosemide and chlorthalidone (water pills)
What this could lead to: If it works, this could point toward a way to help dialysis patients keep some kidney function and reduce fluid buildup between treatments.
What could go wrong: This was a very small pilot study (only 2 participants) that was terminated early, so results are not reliable. It is too early to know if diuretics are safe or effective for dialysis patients.

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Conditions

The condition(s) this trial relates to.

end stage renal failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

END STAGE RENAL DISEASE ON DIALYSIS

Contacts and locations

Locations

University of Alberta

Edmonton, Alberta, T6G 2B7, Canada

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